To cure the spider-monster population of Manhattan, Spider-Man must lead Kid Arachnid, Anya and Harry on a desperate, last-ditch effort to stop the Jackal.
An insecure but courageous and intelligent teen named Peter Parker, a new student of Horizon High, is bitten by a radioactive spider and given powers. He becomes a hero named Spider-Man after the passing of his uncle and he must adapt to this new way of life.