Savannah ("Savi") is a successful career woman working toward the next phase in her life - both professionally and personally - bucking for partner at the law firm where she works while also trying to start a family with her husband, Harry. But when their fertility issues begin to take center stage, Savi finds herself attracted to her flirtatious colleague, Dominic. Savi's free-spirited and capricious baby sister, Josslyn, couldn't be more different, living single, serial dating and partying. A real estate agent, Josslyn has no interest in a committed, long-term relationship.

Their common best friend, April, is a recent widow and mother of a ten-year-old daughter. After she receives her late husband's lucrative life insurance check, she begins getting prank phone calls and tells her closest girlfriends that she's convinced her husband is still alive. Another long-time friend, Karen, is a therapist with her own thriving practice, reconnecting with the girls after her involvement in a complicated relationship with a wealthy, married patient goes too far: She was having an affair with a terminally ill client to whom she had prescribed morphine.

While Karen counsels Savi to hold a beat before confessing to husband Harry about her night with Dominic, Savi gets an entirely different reaction from April. Meanwhile, April investigates a woman's shocking claims that her late husband, Paul, had another life; Joss finds a friend in new client Alex, and Karen warily agrees to meet with Sam Grey.

Tensions escalate at work between Savi and Dom; Joss's new boss, Olivier - very French and very unimpressed with her - gives her an impossible assignment; and Karen continues to be drawn into the dysfunctional Grey family orbit

Savi finds out she's pregnant and knows there's a good chance the baby is indeed Harry's and not a result of the one-time affair she had with Dom. Joss finds herself befriending her gay real estate client, Alex, who has a controlling significant other. April is pressured by the woman who claims she had a child by April's dead husband. Also, despite Savi's advice to the contrary, Karen continues to find herself drawn to the company of Sam Grey, the college-aged son of her dead lover.

Savi is anxious to find out her paternity test results, while trying to hide her pregnancy from Harry. Meanwhile the friendship between Joss and her gay client, Alex, takes an interesting turn when Alex breaks up with her girlfriend; April and Richard are brought closer together when their 10-year-old daughters don't show up for school; and after Karen receives a visit from a private investigator (Gary Dourdan) seeking answers surrounding her lover's passing, she meets with his widow, Elizabeth Grey

Savi desperately tries to make things right with Harry, but he continues to avoid her and discussion of their future; Karen is frightened when, on the heels of the insurance investigation, someone breaks into her office and may have accessed her patient files; April and Richard's romance heats up; and Olivier continues to make Joss's life miserable at the office.

Joss, terribly hurt that Savi hid her pregnancy and her illicit affair from her, moves in with April; Harry and Dominic angrily face off at a social event; Karen meets up again with Detective Newsome, but this time it's personal; and April struggles to put memories of her dead husband behind her so she can move on with a relationship with Richard.

Savi wants to fight for her relationship with Harry, even if the baby is Dom's; April is still reeling from the revelation that her supposedly dead husband, Paul, is actually alive; Karen is surprised when Sam hires her business partner as his therapist and seeks out his mother, Elizabeth, to express her concern; and after an uncomfortable run-in with Alex's ex, Joss wants to redefine her relationship with Alex.

When Savi and Joss's free-spirited, open-minded and often absent mother, Janet, comes for an unexpected visit, she brings big news but also stirs up some long-simmering family tensions. Now that Karen realizes that Elizabeth Grey knew all along about her affair with Tom, she wonders if Elizabeth might have actuallyhuged Tom because of her; and April questions whether she should tell her daughter she's dating Richard, although she has yet to tell Richard about the return of her supposedly-dead husband.

As single mom-to-be Savi begins to grasp that Harry may never be coming back, Dom offers her a shoulder to lean on. April is furious when Paul shows up at Lucy's school and shares her frustration with Richard, who decides to take matters into his own hands. Karen and Sam reconnect after she realizes Savi won't give her information about Elizabeth's lawsuit against her; and at work Joss tries to win over Olivier by helping him impress new real estate clients

Karen begins her deposition into her possible role in the passing and cover-up of her lover, Thomas Grey, where his son, Sam, has promised to be her alibi. Dominic surprises Karen when he brings in private detective Anthony Newsome to testify. After Joss tells Harry that Savi has yet to open up her paternity results, he decides to go to the clinic to find out for himself. And April and Richard, who have broken up, remember they made an amusement park date with their kids they have to keep. Meanwhile, Joss's feelings for Olivier are stirred up when Alex asks her if she misses sleeping with a man.

The judge delivers a shocking ruling in Grey Vs Kim. While the case is closed, there is even more trouble on the horizon for Karen; Paul (Dondre' T. Whitfield) helps a frantic April search for Lucy after the school reports that she's gone missing; Joss tries to salvage her relationship with Alex after she learns Joss slept with Olivier (Mike Dopud); and Savi is receptive to Dom's advances, and accepts the fact that Harry is no longer part of her life... until she learns some disturbing news about the state of Harry's restaurant.

The ladies plan a lavish birthday getaway to Palm Springs for Savi, but the fates conspire against them, as Joss realizes Harry has stolen the test results that would reveal whether he or Dom fathered Savi's baby; April makes a choice on which man to keep in her life; and Elizabeth Grey decides to settle the score, once and for all, with Karen.