In the sixth season premiere, Tree Hill residents make decisions that will change their lives forever. Lucas finally pursues his dream with the woman he loves, Brooke faces a reunion with her mother, Mouth makes a startling revelation, Nathan and Haley encounter a ghost from their past and the news of Dan's accident takes an unexpected turn.

Tree Hill residents are surprised to learn that Luke and Peyton have decided to tie the knot. Brooke tries to adjust to life after the robbery at "Clothes Over Bros". Nathan and Haley receive devastating news and Nanny Carrie's return creates more blanks than answers, after she kidnaps Dan - whose life hangs in the balance.

Quentin's passing brings sorrow to Tree Hill and Haley and Nathan must find the words to help Jamie understand. Brooke continues to hide the truth of her attack which strains her friendship with Peyton and Lucas and Skills meet Quentin's grief-stricken family.

Brooke heads to New York to confront Victoria while Peyton forges a connection with famous musician Mick Wolf, who tells her stories about her parents. Meanwhile, Haley's problems with a student escalate, and Nathan has a strange vision of Quentin.

Tree Hill is in an uproar as Nanny Carrie has finally gotten Haley where she wants her - unfortunately, that means both Haley and Jamie's lives are in danger. Peyton feels threatened when Lucas must reunite with Lindsay for a business meeting. Meanwhile, Brooke's struggle for control at Clothes Over Bros reaches the breaking point as Victoria continues to exert her power by making unexpected and unsettling business decisions.

Everyone's favorite bartender Owen returns to Tree Hill and introduces Nathan to a basketball team called Slamball who want Nathan to join the team. Lucas heads to Nebraska to kick off his book tour, leaving Peyton to deal with the repercussion of learning that Mick is her father. Meanwhile, Mouth continues to do brilliantly at his on-air position in Omaha and Brooke starts to pick up the pieces of her life.

Jamie gets into a fight with a kid named Chuck at school. Haley talks to Chuck's mother but instead of resolving the problem they get into a fight as well. Mouth gets the opportunity to look for an intern. Peyton and Lucas have their first upcoming marriage problem. Brooke continues to care for Samantha, but things get dramatic when she finds out Owen is back in town.

Success is headed for the Scott brothers as Nathan is offered a spot on a major basketball team, and Lucas decides to turn his book into a movie. His decision to ask Lindsay to be a part of the film incites jealousy in Peyton. Meanwhile, Mouth's new intern clashes with Millicent.

Sam teaches Jamie about money. Brooke must decide whether to date Owen again, since he broke her heart the last time. Nathan comes face-to-face with an old rival. Meanwhile, Lucas' novel forces him to make jeopardizing decisions, and Peyton meets the movie producer, Julian.

Lucas' novel makes a comeback and does successfully. Nathan's basketball skills increases. Gigi tries to use her internship to get close to Mouth and Jamie likes Sam's rebellious attitude.

Mouth looks for big news that will shake the town up. Brooke starts having money and men problems. Dan tries to have a relationship with Haley.

Brooke is shocked to find out that Samantha is in her room with a boy named Jack. Along with that, Julian asks her to make some clothes for the movie. Peyton tries to get Mia to focus on her follow-up album. Lucas is excited when he travels to Hollywood to meet the director of the movie. Meanwhile, Nathan gets the chance for a pro-basketball try-out. Haley takes Jamie to his school's talent show and Millicent confronts Mouth about Gigi.

Peyton shares some startling news with Lucas, who discovers that Julian has been keeping another secret about the movie. While searching for runaway Sam, Brooke is forced to confront her lingering feelings over her attack. Nathan struggles with his new professional environment.

News of Peyton's condition spreads like wildfire through Tree Hill. Brooke tries to suss out Julian's intentions. Mouth and Millicent strive to keep their relationship going. Meanwhile, Brooke and Lucas babysit Jamie and his friend when Nathan and Haley spend a night out together.

Lucas and Julian have a difficult time finding the right director for their movie. Meanwhile, a present from Lucas confuses Peyton and Brooke battles with romantic complications.

As Peyton begins to plan the wedding, Lucas attempts to put a cast together for his movie. Meanwhile, Haley is faced with a difficult decision, and Nathan gets great news.

It's a hard day for our couples in Tree Hill, as Peyton and Lucas receive shocking news, and Brooke's relationship comes to a path which might split into two. Mouth and Millie fight to turn the tide for their relationship. Meanwhile, Jamie spends the night with his grandparents while Nathan and Haley celebrate their anniversary.

The production of the film continues to prove challenging as Lucas and Julian face yet another obstacle. Mia also struggles with creative difficulties as she develops her new song, leading Peyton and Haley to try and help her. The kids of Tree Hill confront their own problems when Jamie finds out the truth about Dan and Sam is arrested.

Julian makes an alarming proposition to Brook. Peyton prepares herself for the future while Lucas revisits an important place with Nathan and Jamie. Sam and Jack demand Haley be reinstated back to work.

Lucas struggles to make peace with Peyton's pregnancy troubles. Victoria tries to restart Clothes Over Bros and tempt Brooke back into the business. Haley and Nathan war over how best to educate Jamie.

Nathan and Haley both face their dreams as he questions his ambition to play in the NBA and she receives an offer from Nick Lachey. Meanwhile, Brooke learns something that could change Sam's life forever, Jamie attends his first school dance, and Lucas and Peyton take a road trip.

The families of Tree Hill draw closer as Lucas bonds with Jamie while working on Peyton's car, Sam develops a connection with Victoria, and Brooke and Haley throw Peyton a baby shower. Meanwhile, Nathan's ambitions seem closer than ever when he learns that an NBA scout will be watching his next game.

Lucas and Peyton's wedding day finally arrives, bringing some surprise guests along with it. Haley finds herself playing an unexpected role in the ceremony, as Skills and Brooke try to control Jamie and Nick. Meanwhile, Nathan continues to hope to be drafted into the NBA.

Tree Hill bids goodbye to the past while anticipating the future: Lucas and Peyton prepare for the birth of their child with the help of a surprise visitor, Dan nears his end, and Brooke works with Victoria to relaunch Clothes Over Bro's. Meanwhile, Nathan returns to Tree Hill to face Haley and Jamie after being released from the Chiefs.