With the Contest in Fallabor Town over, the gang are now headed to Lavaridge Town so Ash can battle for his next Gym Badge. However they soon re-encounter Kazuchi, who taught his Plusle and Minun the Helping Hand attack and as a result was invited to join a group of cheerleaders. Soon the gang are in the company of said cheerleaders and their leader, but it seems this group aren't fair when it comes to Pokemon battles...
A young boy named Ash Ketchum embarks on a journey to become a "Pokemon Master" with his first Pokemon, Pikachu. Joining him on his travels are Brock, a girl-obsessed Rock Pokemon Trainer, and Misty, a tomboyish Water Pokemon Trainer who may have a crush on him. Ash and Co. end up traveling through various regions, including Kanto, the Orange Islands, and Johto, and then enter the Pokemon League competitions there.
Along the way, they run into many confrontations with Jessie, James, and Meowth, a trio of Pokemon thieves who are apart of an evil organization called "Team Rocket". But every time Team Rocket try to do their evil deeds, they fail thanks to Ash and his Pokemon.