While walking through a dark forest, a Skarmory attacks the gang. When Skitty pops out it's Pokeball, May rushes to save it and ends up being carried off by the Steel Bird Pokemon, carrying her over a huge fence and dropping her off in a grassy area. While there, May encounters a Bulbasaur and becomes friends with it, but is soon attacked by other Grass Pokemon whom are extremely distrustful of humans. Meanwhile Ash, Brock and Max appeal to the Forest's protectors to allow them entry to rescue May, and when they are disallowed, the three decide to sneak in and save their friend...
A young boy named Ash Ketchum embarks on a journey to become a "Pokemon Master" with his first Pokemon, Pikachu. Joining him on his travels are Brock, a girl-obsessed Rock Pokemon Trainer, and Misty, a tomboyish Water Pokemon Trainer who may have a crush on him. Ash and Co. end up traveling through various regions, including Kanto, the Orange Islands, and Johto, and then enter the Pokemon League competitions there.
Along the way, they run into many confrontations with Jessie, James, and Meowth, a trio of Pokemon thieves who are apart of an evil organization called "Team Rocket". But every time Team Rocket try to do their evil deeds, they fail thanks to Ash and his Pokemon.