Alas, it is just another day in the life of Team Rocket, as they make a landing following a recent blast off, except this time they all have Afro-Hairstyles courtesy of Pikachu's Thunderbolt! Whilst arguing amongst themselves whose fault their latest trip through the skies was, they notice a huge mansion... so naturally they decide to rob the joint. Meanwhile Ash and the gang have their own Afro's, but while they continue the road to Fortree City, a rainstorm starts up, and while it puts their hair back to normal, they have to find shelter, and come across the same mansion. After entering May and Max have yet another argument, but when Max goes missing May and the others need to find him, not realising he's made friends with one of the mansion's inhabitants, a friendly Shuppet!
A young boy named Ash Ketchum embarks on a journey to become a "Pokemon Master" with his first Pokemon, Pikachu. Joining him on his travels are Brock, a girl-obsessed Rock Pokemon Trainer, and Misty, a tomboyish Water Pokemon Trainer who may have a crush on him. Ash and Co. end up traveling through various regions, including Kanto, the Orange Islands, and Johto, and then enter the Pokemon League competitions there.
Along the way, they run into many confrontations with Jessie, James, and Meowth, a trio of Pokemon thieves who are apart of an evil organization called "Team Rocket". But every time Team Rocket try to do their evil deeds, they fail thanks to Ash and his Pokemon.