After a winter abroad, Hank returns to the Hamptons to celebrate the latest addition to the HankMed family. Evan and Paige take a hands-on approach to their marriage. Later Evan hatches a plan to make Hank stay in town after a saxophone player falls ill. Meanwhile Divya experiences the joys of motherhood and a mysterious party guest brings surprising news for the Lawson family.

Hank worries a rising tennis star's health may prevent her from taking her career to the next level, while a fellow pro at her club may have fallen ill from an unexpected source. Later Hank and Evan adjust to a startling revelation about Eddie's past. And Evan and Paige reach a new milestone. Elsewhere Jeremiah finds peace in an odd place.

Hank, Evan and Paige try to help Eddie have a relationship with Emma; Hank treats a private investigator; Divya must find a nanny; Jeremiah makes a friend.

Hank travels to Monte Carlo and finds himself in the middle of a plot to rid Boris' bank of a shadowy depositor. Back in the Hamptons, Divya and Jeremiah treat a group of firemen who have fallen mysteriously ill. Paige and Evan find themselves in need of a new place to live, and the most convenient solution may bring its own set of challenges.

After reading about her struggle online, Evan reaches out to a woman with a mysterious illness in the hope that Hank can finally give her a diagnosis. Paige and Russel's professional lives take an unexpected turn, and their new client could be a goldmine or a dangerous problem - especially when he becomes a HankMed patient. While Evan and Jeremiah realize they'll have to go to battle with Symphony if HankMed is to survive the summer, Hank's watchful eye on Emma helps him win back a former patient.

Divya treats a NASCAR crew chief who channels his anxiety into a dangerous habit; the chef at Ray's seems to be getting drunk on the job, but Hank suspects something else; Evan finds a promising space for the lab, but Jeremiah has concerns.

Hank and Divya treat a house-sitter; Jeremiah treats a burlesque dancer and gets close to her roommate; Paige makes an important discovery; Emma becomes a tipster for a gossip site.

As a new mother, Divya finds herself bonding with a HankMed patient who is struggling to get pregnant. Hank reignites his romance with a woman he met in Europe when she arrives in the Hamptons, and Divya worries about Jeremiah's relationship with Viviana. Emma is the new it-girl on SnarkHampton and gets invited to one of the hottest parties of the summer, and Paige and Evan enlist Bob to help with their issues with Russel.

Hank treats a perfumer who is losing the sense of smell; Evan and Ray hold a grand opening for HankLab; Divya tries to protect Jeremiah.

Hank and Boris meet a potential trial patient in Argentina; Divya meets Sashi's grandmother; Russel tries to make amends with Paige; Evan strives to expose Oz.

Despite their strained relationship, Divya and Jeremiah work together to treat a model who is struggling to eat. After Ray's past catches up with him, Evan tries to distance himself from their partnership but it proves to be harder than he expected. Hank and Boris return from Argentina with an idea to enlarge the scope of Boris' foundation, and Emma violates her brothers' trust.

Hank treats Cinco when his sore wrist turns out to be more complicated than a simple sprain. Evan and Paige help Emma set a trap to catch Oz. Divya and Jeremiah treat a boat-builder who resents being left behind when his business partner takes a job sailing around the world. Hank helps Charlotte adjust to regaining her vision but the learning curve is steeper than either of them anticipated. Meanwhile, Boris takes a major step towards expanding his foundation.

Hank and Evan search for Emma after her unexpected disappearance. Evan struggles to understand why Hank refuses to join Boris' latest endeavor. Meanwhile, as Paige and Evan finally are ready to move on from therapy, they discover some surprising news about Bob. And while Jeremiah tries to accept the changes Viviana is making in her life, he realizes he needs to make some changes of his own. Elsewhere, Divya faces a new hurdle in her custody battle, while Boris worries his disease may be catching up with him.