Harry becomes an overnight father figure to nine-year-old Billy and teenage Anastasia, who both seem to be the product of Harry's past foray into sperm donation. Meanwhile Harry meets Rose, a beautiful, if neurotic, single woman who's out to have a baby on her own, and who believes Harry may have what she needs to get pregnant.
Harry helps Billy's moms, Zoey and Michelle, to encourage Billy to be cooler at school. Meanwhile Jonathan and Janet fear their daughter Anastasia may be failing French, and administer an I.Q. test to Harry, fearing she got the 'dumb gene' from him. Harry and Rose square off about the future of Rose's potential child.
Harry signs Billy up for Rhythmic Gymnastics, so that Harry can hook up with the hot new gymnastics teacher. Meanwhile Jonathan offers Harry 00 to disappear from his daughter's life. Rose strikes up a friendship with Irene, who Harry fears will tell Rose all of Harry's dirty secrets.
Double-booked, Harry must decide between scoring with a hot fashion model or attending his baby's first ultrasound.
Zoey pressures Billy to become the best at his school's grapefruit sales competition and Anastasia pawns off her homework on Rose, who tests her maternal instincts on an electronic baby.
Harry finds out the truth about Jonathan and Janet's sex life. Plus Rose decides to hide her pregnancy from her boss.
Anastasia discovers Jonathan is part of "The Movement". Rose has a new boyfriend and Harry is determined to find out what his motives are.
Harry comes down with symptoms of Sympathetic Pregnancy while Janet realizes that Jonathan has been seeing a rival psychologist.
Harry helps Rose to make friends in her new birthing class, while Janet and Jonathan fight for the chance to be involved in Anastasia's prom.
Harry coaxes out Rose's bachelor side when they are forced to share an apartment. Zoey's grandmother plays a visit, and Rachel goes behind Jonathan's back in an attempt to get a good deal on a car.
Harry lies about having a relationship with Rose to score with a home-wrecker; Jonathan and Janet attempt to connect with Anastasia online.
Rose lies to make a preschool waitlist; while Zoey and Michelle attempt to give Billy 'The Talk'.
Roses's pregnancy nears full term, prompting Zoey and Michelle to contemplate whether they will ever want another child of their own.