The Sliders arrive on a world in which the United States is a monarchy, and Rembrandt is Duke of Hemmingshire. When Rembrandt sees Danielle, a woman he recognizes and who in actuality is the Duchess of this world, apparently about to give birth, he goes to help. However, what he doesn't know is that the husbands give birth on this world.
In his basement in San Francisco, boy-genius Quinn Mallory unlocks the doorway to an infinite number of Earths. During a test run, Quinn invites co-worker Wade Wells and his teacher Professor Maximillian Arturo to see his new invention. But an increase in power and an early departure leave all three, plus a washed-up soul singer named Rembrandt "Crying Man" Brown, lost in a parallel world. Now they must "slide" from world to world, not only adapting to their changing surroundings, but also trying to get back to their world. Will they ever make it home?