Voyager discovers energy reading believed to be emanating from the female Caretaker who had been the companion of the male Caretaker that brought Voyager to the Delta Quadrant ("Caretaker"). The remains of the male Caretaker act as a beacon and lead Voyager to a space station with a group of psychically advanced Ocampa being protected by the female Caretaker, named Suspiria.
While chasing a renegade Maquis ship in the Badlands, the USS Voyager and the Maquis ship they are chasing are pulled into a vortex, which sends them instantly to the Delta Quadrant. However, after the destruction of the device that transported them to the Delta Quadrant, the crew of Voyager and the crew of the Maquis ship must join together to fight their way back to their home in the Alpha quadrant, which is many years away. They will meet many foes and many obstacles along the way, but they will also bond as a crew, between those of the Maquis and those of Starfleet.