Stardate: 49504.3 Voyager answers the distress signal of a Vidiian ship and transports the lone occupant to sickbay. The occupant is suffering from the Phage, and near passing. The Doctor puts the unconscious patient into a coma, but then he links her brain's synaptic activities to a holodeck created virtual rendition of the Vidiian without the disease. When she wakes, the Vidiian gazes upon a healthy face she had not seen since she was seven years old. However, the holo-image will only keep her alive for a short period of time. The Vidiian, a hemotologist, and the Doctor work together to restore her synaptic functions to her old body before her brain waves disappear and she dies.
While chasing a renegade Maquis ship in the Badlands, the USS Voyager and the Maquis ship they are chasing are pulled into a vortex, which sends them instantly to the Delta Quadrant. However, after the destruction of the device that transported them to the Delta Quadrant, the crew of Voyager and the crew of the Maquis ship must join together to fight their way back to their home in the Alpha quadrant, which is many years away. They will meet many foes and many obstacles along the way, but they will also bond as a crew, between those of the Maquis and those of Starfleet.