When an alien attaches itself to B'Elanna's nervous system, the Doctor enlists the help of a holographic recreation of the Cardassian Dr. Crell Mossett. She refuses all treatment when the Bajoran crew informs her that this doctor was responsible for sadistic war crimes during the occupation.
While chasing a renegade Maquis ship in the Badlands, the USS Voyager and the Maquis ship they are chasing are pulled into a vortex, which sends them instantly to the Delta Quadrant. However, after the destruction of the device that transported them to the Delta Quadrant, the crew of Voyager and the crew of the Maquis ship must join together to fight their way back to their home in the Alpha quadrant, which is many years away. They will meet many foes and many obstacles along the way, but they will also bond as a crew, between those of the Maquis and those of Starfleet.