Still reeling from the revelation of the truth behind his existence, Swamp Thing goes on the offensive against Ellery's mercenary team hunting him; Abby comes up against Jason Woodrue, who has crossed the line to save his wife's life.
When CDC researcher Abby Arcane returns to her childhood home of Houma, Louisiana, in order to investigate a deadly swamp-borne virus, she develops a surprising bond with scientist Alec Holland - only to have him tragically taken from her. But as powerful forces descend on Houma, intent on exploiting the swamp's mysterious properties for their own purposes, Abby will discover that the swamp holds mystical secrets, both horrifying and wondrous - and the potential love of her life may not be dead after all.