Adam surprises everyone when he fulfils one of Cathy's wishes. Cathy's estranged Dad visits her. Andrea gets the opportunity of a lifetime. Sean has mixed feelings about his impending kidney surgery.
The Big C delves into the emotional ups and downs of a suburban wife and mother forced to face reality yet also find the light side in a dark situation. A metaphor for the way we all should live, yet rarely do, this is a journey about how to seize the day.