Cesare burns Constanzo's palace in order to contain the plague. Lucrezia, aware that the political wind has changed towards France, seeks a Neapolitan power base for herself and her family. Lucrezia blackmails Prince Raphael and Prince Frederigo replaces Ferdinand as King.
Set in 15th century Italy at the height of the Renaissance, The Borgias chronicles the corrupt rise of patriarch Rodrigo Borgia to the papacy, where he proceeds to commit every sin in the book to amass and retain power, influence and enormous wealth for himself and his family.
Aiding him in his endeavors are his sons Cesare, a ruthless operator who yearns fruitlessly to be released from the priesthood, and Juan, a feckless dilettante whom Rodrigo appoints to head the papal armies. Daughter Lucrezia and son Joffre are married off in early adolescence to members of powerful rival families - pawns in their family's fortunes.
Waging their own heated contest for Rodrigo's affections are Vanozza, his long-time mistress and mother of his children, and the younger Giulia Farnese, whose cunning is matched only by her astonishing beauty.
The Borgias - Lucrezia's Gambit Synopsis and Schedule