Ethan's medical knowledge and connections are put to the test when Lina is rushed to the hospital and her twin, Kat, is unable to get an update on her from the staff. Meanwhile, Perry and Holly, who are trying to get their daughter, Oprah, into a prestigious school, have brunch with Kyle who works at the school. While at brunch, Kyle relives how he broke Holly's heart at the prom.
A group of twenty-somethings who were third-grade classmates are reunited at a surprise party 20 years later. What will happen when they find out what each other's lives are like now?