On the eve of 1985, a worn-out Vincent reconnects with his ex-wife, Andrea as his open relationship with Abby grows more distant. Despite becoming a family man, Frankie continues his risky side hustles. With the newly dominant VHS format shaking up their industry, Candy and Harvey travel to Las Vegas for an adult film convention where they disagree on how to navigate a fast-changing future. Now a bartender at the Hi-Hat, Loretta becomes an active member of Women Against Pornography.

Frankie takes his amateur porn business to the next level and ends up in a confrontation with Rudy, who pushes Vincent to up his profits. Candy brainstorms a new film based on the experiences of her fellow sex workers and finds that her new beau Hank is not shaken by her past. Abby and Loretta take care of Shay when she shows up to the Hi-Hat in bad shape. Lori is advised be more compliant after she dares to stand up for herself on set. Alston is tasked with finding the mysterious owner of a prime piece of Midtown real estate. With the future of his businesses up in the air, Paul worries about his partner Tod's health.

Abby befriends a graffiti artist named Pilar and takes a surprising trip downtown. Candy sets a firm line with Hank when it comes to money. As Todd's health worsens, he reexamines his priorities and asks for Paul's support. Melissa is forced to face her past. Alston explores different strategies for getting a shady SRO owner to sell. Bobby pays Joey a visit on Wall Street as Joey's latest money-making scheme grows bigger. Tensions rise between Frankie and Rudy as a buyer complains about Frankie's product.

Lori returns to New York for an audition and runs into some familiar faces. While searching for actors for her new film, Candy speaks to her critics at a Women Against Pornography meeting. As things heat up with Jennifer, Alston takes a drastic step to deliver for Goldman. Melissa leaves the city. Abby grows closer to Pilar as her relationship with Vincent wanes. Vincent and Frankie celebrate an eventful birthday.

With his club shuttered, a distraught Vincent follows a lead down a dangerous path. Paul reaches out to Tod's parents. Candy battles Harvey over her latest script and reunites with her estranged son, Adam. Lori hits the feature dancing circuit with mixed results. Abby reflects on her choices when she gets an unexpected visitor. Bobby does right by Black Frankie. Alston defends the plan to clean up Midtown. Gene reckons with his conflicted personal life.

In the wake of a personal loss, Candy finds the emotional core of her latest movie. Abby confronts Vincent after she makes an alarming discovery. Paul turns to activism as the AIDS epidemic continues to ravage New York's gay community. Vincent tips off Rudy to Tommy's disloyalty. Lori realizes she's on her own when both Greg and Kiki let her down. Bobby learns why the women who worked for him have abandoned the French Parlor.

A struggling Lori turns to Candy for help before revisiting The Deuce. Candy makes a surprising deal to secure funding for her film. Abby takes a stand against the latest phase of Midtown redevelopment. After a difficult visit with Mike, Vincent is approached by a candid Tommy, who explains the new world order. Bobby realizes that times have changed and considers Joey's latest money-making scheme.

Big changes come to The Deuce as Gene sees opportunity in the city's public health crisis. Vincent looks to get out from under the mob's thumb and makes peace with Abby, who decides to pursue a new future. Candy makes a critical choice in her relationship with Hank. Harvey speaks his mind about Candy's film. Alston recognizes the truth of Midtown's redevelopment. Melissa makes a commitment, while Loretta takes on a big responsibility.