As Mindy and Casey adjust to their new life in Haiti, their blissful time is cut short when Mindy suddenly falls ill and is airlifted back to New York. Meanwhile, Schulman & Associates welcome their new resident OB/GYN Paul Leotard, a charming, former model who also happens to be a sex therapist and offers sex therapy advice to Danny and Christina.
As Mindy adjusts to her long-distance relationship with Casey, she also must adjust to the fact that she is no longer the office's "Dr. L" - her office, patients and dignity have been overtaken by Dr. Paul Leotard - so she challenges Paul to get her former life back. Meanwhile, Danny has a new extracurricular activity following his breakup with Christina.
After returning from Haiti, Casey has an identity crisis and thinks being a disc jockey might be his new calling. When Mindy and the office go to a music festival for their "work retreat" to see Casey perform, the substance-filled surroundings lead to a series of disasters. Meanwhile, back in New York, Jeremy hires a new doctor, whom Mindy doesn't particularly like after he saves the day during an emergency delivery.
According to Morgan, anyone who sleeps with him will find the love of their life immediately afterward. Curious to test this theory, Mindy takes Morgan up on his offer, but backs out at the last minute, humiliating Morgan and prompting him to sue Mindy for sexual harassment. In order to get out of the lawsuit and get back into Morgan's good graces, Mindy makes him an offer he can't refuse.
Mindy hits it off with a journalist named Jason (guest star Feldman), but Jason is a bit snobbish and finds Mindy to be too mainstream. To show that she's more cultured than he thinks, Mindy invites Jason to Christina's (guest star Chloe Sevigny) art show, where nude photos of Danny (Chris Messina) are on display.
Mindy's excited to join the guys for a "boy's night out" at MoMA, but quickly realizes she misunderstood their plans: They're not going to the museum, they're going to an MMA fight and Mindy couldn't be further out of her element.
Danny tells Mindy that she's too picky and judgmental of other people. So she makes it her mission to prove him wrong, and goes on a date with her complete opposite: a wild and crazy skateboarder named Graham. Meanwhile, Jeremy receives a visit from his father, who seems to prefer Peter over his own son.
When Mindy tells Danny she has a crush, he thinks she's talking about him instead of Cliff, the lawyer. Meanwhile, Morgan and Peter find Mindy's phone and respond to a text from Cliff, which starts off innocently, but escalates into something that may lead to unintended romantic consequences.
One of Danny's patients is a mommy blogger, so he invites her to write about Schulman & Associates on her website, only to find out that she is actually a white supremacist and paints the practice in a racist light. Desperate to control the situation, the team hires PR guru Priscilla, who begins to give Danny media training but ends up seducing him.
When Mindy's cheating ex-boyfriend Josh invites her to his wedding, Mindy panics to find a date and begrudgingly decides to take Peter, who is actually a great wedding date until he makes one big mistake. Meanwhile, Danny's kid brother Richie is in town to make a big announcement.
Mindy plans an office Christmas party for the entire building, so she can spend more time with Cliff. However, things don't go Mindy's way when Brendan Deslaurier's date steals Mindy's thunder by performing a seductive "Santa Baby" dance for the party guests.
In an attempt to get in shape before a weekend away with Cliff (guest star Glenn Howerton), Mindy convinces Danny to be her personal trainer. Meanwhile at the office, Peter finds himself in over his head when he has to act as managing partner while Jeremy is out sick.
Jeremy sends Mindy, Danny, Peter and Morgan to Los Angeles to receive cosmetic injectables certification. Once they arrive, Peter attempts to track down the object of his affection, Maria Menounos, and Mindy runs into Casey.
After Cliff breaks up with Mindy for lying about seeing Casey in Los Angeles, Mindy is more determined than ever to win him back. However, instead of taking Mindy to the airport, Danny tricks her into going with him to the desert to see his dad.
Mindy and Danny confront the consequences of their kiss. Meanwhile, Jeremy and Peter devise a plan to poach patients from a competing practice that has shut down.
Mindy discovers an incriminating video of herself that is floating around the internet, and she enlists the help of Peter to keep it from falling into the wrong hands.
Mindy and Danny try their hand at dating. But they discover that redefining their relationship isn't as easy as they thought it would be, especially when the pharmaceuticals representative whom Danny used to date re-enters the picture. Then, a high-profile doctor and Mindy's idol, tries to poach her.
Mindy and Danny try their hand at dating. But they discover that redefining their relationship isn't as easy as they thought it would be, especially when the pharmaceuticals representative whom Danny used to date re-enters the picture. Then, a high-profile doctor and Mindy's idol, tries to poach her.
Peter encourages Mindy to think more like a man. To test his advice, they head out to a bar, where they meet Lee, a smooth-talking first-grade teacher who is up to no good. Meanwhile, Danny tries to give relationship advice to Tamra.
Mindy has a run-in with the law when a surly police officer admonishes her for giving his young daughter birth control pills. Meanwhile, Danny befriends a rabbi who offers to refer his congregation to Schulman & Associates because he thinks Danny is Jewish.
Danny offers Mindy the opportunity to buy the other condo he owns in his building, but gets jealous when she begins to date Charlie, the police officer. Meanwhile, Peter dates a brain surgeon whom he fears may be too mature for him.
Mindy thinks she's met the man of her dreams after he writes a description of their encounter in a New York newspaper, leading to a surprising reveal.