When a young boy comes into the hospital with a rare disease which leaves his bones incredibly fragile, Cade's father, Ian, scrubs in to assist in the surgery, leaving Cade all on her own in her recovery. With his clinical trial officially being declared a success, Devon has some huge decisions to make about the future of his career. Meanwhile, Billie struggles with some new feelings.
Conrad Hawkins is one of Chastain Park Memorial Hospital's best doctors. Charming and arrogant, Conrad likes to take an unconventional approach whenever possible and believes it's his personal duty to shatter the romantic illusions of the first-year residents. Dr. Devon Pravesh is an innocent idealist who leans on his finely tuned moral compass, but with Conrad's help, he begins to realize that the practice of medicine is a business, like any other, with less-than-angelic patients and fallible doctors. Lives may be saved or lost, but expectations will always be shattered.