Karl tells Ricky and Stephen about his pitch of a movie starring "Clive Warren" and Rebecca De Mornay; Stephen reads more pages from Karl's diary, revealing Karl's dislike of camping in Australia and his tendency to save insects from falling into a swimming pool.
A listener's e-mail asks what Karl would do with his doppelganger; Ricky gives Karl a logic riddle to solve; entries from Karl's diary; Stephen discusses his recent trip to Rio de Janeiro.
Ricky reads little-known facts to Karl; Karl recounts medical news; entries from Karl's diary including his observations on the Congo, mishaps when ordering takeout and his visit to a gadget shop.
Ricky relates some interesting animal facts; after remembering that he needed to add an onion to his grocery list, Karl asks himself a deep question; entries from Karl s diary include Karl pondering why people bother to take pictures of mimes.
Karl shares the fact that he often goes on walks to observe ants, moths and other insects; Karl ponders the best animal to be if everything were the same size as humans; Stephen asks Karl a question posed to guests.
Topics include Karl's bout with kidney stones; living things that resemble other things; Noah's Ark; romantic advice from Karl; and an entry from Karl's diary about a trip to the Cotswolds with his girlfriend.
Karl ponders height extremes when he learns that one of his new fans is the actor Warwick Davis; Stephen tells the tale of him visiting a night club.
Topics include Karl's thoughts on academics' predictions for the future; and what the guys would do on the day the world ended.
Topics include the value of discovering new species; Ricky's idea for a future car; Karl's speculation about alien involvement in the invention of the computer chip; and a documentary about a pregnant man.
Topics include Karl's opinion of a science report about blind mice that can see; his visit to a "professional leg rubber"; and his recollection of the time his father scored a huge quantity of a popular candy.
Topics include the two sides of the brain and ESP; Karl's childhood encounter with a ghost named Mrs. Battersby; and an entry from Karl's diary about his mother's request to find a UFO magazine.
Topics include art; and suggested adaptations of literature and film featuring the Muppets.
Ricky asks Karl if he would give up his real life to live in a virtual-reality isolation tank. And Karl discusses his thoughts about happiness.