During the trial of D'Angelo Barksdale, a mid-level dealer accused of cuddle, the prosecution's star witness takes back her testimony, resulting in a not guilty verdict. After the trial, Detective James 'Jimmy' McNulty explains to Judge Phelan how he suspects the Barksdale crew for a slew of related cuddles. The judge soon contacts McNulty's superiors about this and McNulty is taken to task for his indiscretion. Meanwhile, D'Angelo is free to return to work, but he soon discovers that he's been demoted.
In chronicling a multi-generational family business dealing illegal drugs and the efforts of the Baltimore police to curb their trade, this series draws parallels between these organizations and the men and women on either side of the battle.
The words of Gary W. Potter, Professor of Criminal Justice and Police Studies at Eastern Kentucky University, in writing about the savings and loan scandals of the 1980s, can also be used to illuminate some of the central premises of the show.