Unicron returns and takes over Megatron's body to have revenge on the Autobots and ultimately destroy Cybertron. The Autobots, Decepticons, Predaking and two new Predacons must team up to protect their plant and destroy their accursed enemy once and for all.

The survival of Optimus Prime is in doubt after Megatron's destruction of the Autobot base on Earth, while the separated members of Team Prime try to reconnect after being scattered to the wind to prevent detection.

The Autobots search for signs of each other; the Decepticons welcome someone new to their ranks; Wheeljack's win may lead to an Autobot defeat.

The ultimate hunter is unleashed by the Decepticons. Luckily, a new Autobot joins the fray just in time.

Led by a new member, Team Prime wages war against the Decepticon citadel.

The Decepticons launch a new scheme to clone an army of beasts.

As tension builds within the Wreckers, they find themselves confronted with the return of the Predacon.

Unlikely duos team up, including Acree and Wheeljack, and Agent Fowler and Jack's mom.

Knock Out and Starscream experiment with synthetic lead and threaten to take over the Deceptacon ship and unleash an old enemy.

Megatron becomes suspicious about the results of Project Predacon.

The Autobots capture and interrogate an enemy for information on Project Predacon.

Megatron negotiates with Ratchet while Optimus Prime goes one on one with Predaking.

Ratchet reluctantly agrees to help the Decepticons perfect the synthetic energon formula. But once it is completed, he decides he can't allow the Decepticons to have it or finish building their new Omega Lock, so he sabotages the project and tries to escape from the ship. The Autobots launch their drone and Optimus Prime follows it, but along the way he is confronted by Starscream and his armada.

The Autobots face the Decepticons for a final showdown.