Sara Collins, the beautiful young wife of prominent Georgia Senator Jeffrey Collins, inexplicably vanishes. As the search for Sara unravels one of the nation's most prominent families, it also exposes evidence that could rock the foundations of American society. Through the eyes of Senior FBI Agent Graham Kelton, ambitious reporter Judy Nash and the distraught members of the Collins family, viewers will journey inside a sensational, thrilling national soap opera. Kelton, partnered with determined Agent Len Mei, uncovers enigmatic clues that suggest Sara's disappearance may be part of a large, sinister conspiracy. At the Collins home, Jeffrey and Sara's dutiful son Max is keeping secrets of his own, while his rebellious sister Marcy is on the verge of eloping with her sketchy boyfriend Ben, whose motives are questionable. Just when things couldn't get any more chaotic for Senator Collins, his ex-wife Jessica Nevins and a man from Sara's past, Peter Manning, mysteriously surface.
Vanished centers on the search for Sara Collins. She's the wife of Senator Jeffrey Collins. Sara vanishes and the FBI lead by Agent Graham Kelton is on the job, but before they can find her they need to find out who she really is.
The mystery surrounding the disappearance is seen through the eyes of the FBI, members of the family and a reporter trying to get the story of her career.
The search for Sara will expose many secrets. Nothing is as it seems. Everyone is a suspect because of their secrets.