The school is still in mourning following Tom Clarkson's passing as the new term starts. Audrey finds herself out of her depth after she suspects new pupils, Lenny and Lisa, are being neglected. New teacher, Sue Spark, feels the pressure on her first day. Simon has a secret he is keeping from the rest of his colleagues.
The day from hell for new science teacher, Sue Spark, leads to a shady alliance with a student. George introduces the school to his new Mandarin teaching assistant, and wife, Princess Windsor, who is immediately popular with some of his class. Elsewhere, the pupils revolt against Christine's cuts.
Princess is feeling increasingly irritated by George, which ends up leading to a temptation with one of his pupils. It is the battle of the sexes as Simon's Apprentice competition takes over the school. Kevin suffers with itchy feet. Audrey believes that she's made a new friend.
It is the launch party for Waterloo Junk-tion and Rhiannon's determined to bag herself a date. George attempts to sort things out with Princess but learns that it might be too late. Audrey finally works out that her new friend Moira isn't what she seems to be.
Audrey has worked out the twin's plan to try and scam her out of money, and calls in their estranged grandfather for support. George is upset about Princess's exit and Christine finally realises that he can't teach Mandarin without her. Connor finds some hidden talents in the Home Economics class.
Grantly returns to teaching at the school and soon finds the place as chaotic as ever. Kacey prepares for her first boxing match. Barry sees it as an opportunity to make some money. Sue starts to take tranquilisers to help get her through the day.
The pupils and staff attempt to come to terms with the loss of Grantly. Nikki has a really difficult decision to make after her estranged daughter shows up at the school. Kacey is excited about going to America and decides to try and take matters into her own hands after Carol refuses to let her go.
It's Living History Week at Waterloo Road and the whole school is in high spirits but it's not long before the day takes a turn for the worse when three pupils take seriously ill. Simon and Sue up the ante in their campaign against Christine and Kevin woos Dynasty back into his arms.
After Olympic boxing champion Nicola Adams pays a visit it manages to restore Kacey's confidence in her own abilities. Lenny becomes friends eith the new supply teacher but panic follows after it's discovered that the teacher is not all that he seems.
Simon and Christine are feeling the pressure as they prepare to battle it out for the head teacher position. They end up clashing over how to deal with a pupil who is being bullied. Simon is having second thoughts about his upcoming wedding to Sue. The school is shocked after Kacey's boxing fund is stolen, putting her place at the training camp in doubt.
A beautiful new girl enrols in the school but doesn't waste any time in causing mayhem amongst both staff and pupils with her outrageous behaviour. Simon launches his new Resilience Education plan to make the pupils tougher and Nikki returns from the holidays with a new love interest.
Carol Barry's money-making scheme takes her down some unexpected paths. Connor is offered his dream job but has to try and convince his mother to let him go. Nikki and Vix take a huge step forward in their relationship.
Gabriella continues to end up having more enemies than friends. Christine finds it hard to deal with her emotions as Connor leaves for London . Nikki is concerned about Eve's reaction to news of her engagement.
Lenny gets carried away with the Resilience Programme and causes widespread panic when he accuses the local shop of shady dealings. George and Carol's flush of new love is marred by the arrival of his very opinionated mother. A vindictive Barry Barry visits Waterloo Road.
It's time for the long-awaited Resilience Camp but it seems that some of the students and the staff have ulterior motives for going on the trip. Gabriella ups the ante in her obsessive pursuit of Hector and Christine is forced to confront her feelings about George.
Chalky makes a return to Waterloo Road to lend support to Kevin ahead of his bursary interview, but events take a dire turn when Kevin is suddenly taken ill. Nikki tries in vain to hide her betrayal from Vix and Audrey vows to support Lula when she's threatened with deportation.
George is left in charge while Christine has a day off but is soon out of his depth when Audrey rouses the school in a mass protest against Lula's deportation. Barry wants to discuss his future with Gabriella and Dynasty is distressed at Kevin's condition.
Dynasty has to deal with a shocking dilemma after she finds out how Barry is making money. Christine is not happy to discover Darren with inappropriate images again but finds out some shocking truths after she visits his home.
Christine makes a series of extremely bad decisions leaving her job and her future hanging in the balance. Kacey Barry makes a welcome return to the school but Gabriella is furious to find herself pushed out of the limelight.
Christine attempts to deal with the repercussions of her drink-driving offence. Kacey is selected to take part in the Commonwealth Games. Gabriella soon puts an end to her happiness though. Nikki's future at the school is thrown into uncertainty.