Grace returns from her European travels a new woman, but her elation is short-lived when she receives life-changing news. Karen teaches Will how to be better at phone sex. Jack has a yard sale to discreetly get rid of Estefan's annoying cuckoo clock.
When Grace admits she's not sure who's the father of her baby, Karen orchestrates a "Mamma Mia" situation with the potential baby daddies. Will worries what will happen if he has a straight son and enlists Jack to help him prepare.
Will discovers a way to finally get back at Jack for years of mocking his hairline. Grace is determined to prove to Mrs. Timmer she's strong enough to handle being a single mother. Karen squares off against Stan's brother in a poker game.
Will and Grace get competitive over whose process of having a baby is more difficult. Jack helps Karen prove that she'll be a competent owner of her new baseball team, but Karen realizes that an old acquaintance may be the help she really needs.
In the aftermath of Will and McCoy breaking up, Grace and Jack hire the Grief Panda to help Will process his pain. With Karen completely occupied with her new baseball team, Grace believes that she has to fire Karen in order to set her free.
Committed to becoming a father on his own, Will meets a potential surrogate with stellar reviews, but her lifestyle choices give him doubts. in order to gain entry to AnnieCon, Grace pretends to be a formerly famous Annie.
Grace and her neighbor give their romance another shot. However, an embarrassing incident puts Grace's relationship, and her dignity, in jeopardy. Will decides it's time for Jack to grow up and cuts him off financially.
When Larry warns Will and Grace about the difficult entry process into the elite school they both want their kids to go to, they set out to prove that their child would be the better candidate. While helping Jenny with her ASMR livestream, Jack unwittingly creates problems between Karen and her "booty buddy", Luke.
Will and Grace decide to intervene when they discover Grace's niece is dating a bisexual man. Jack gets permission from his husband to sleep with his celebrity hall pass. Karen struggles to adapt when her assistant books them on an economy flight.
Marilyn goes behind Grace's back to fix her up with a beagle-breeding couple interested in adopting Grace's baby. Will helps Karen deal with a PR nightmare. Jack and Estefan go to extreme lengths to get rid of a mouse.
Grace and her neighbor, James, give their relationship one more shot, but when James invites Grace to his job at the aquarium, she endangers his job and a species. Jack takes Will to an unexpected place to blow off steam - church.
Karen introduces Will and Grace to the new love of her life, Phil, but Will and Grace become suspicious that he has sinister intentions. When Miss Coco Peru tells Jack that he's closing down his bar, Estefan encourages Jack to become its new owner.
Will and Grace race to save Karen when they think she is in danger after her new boyfriend takes her to a cabin in the woods. Jack makes up a story to a snobby reporter in order to keep his new bar relevant after its previous owner steps down.
Jack helps Karen sneak into the manse to retrieve her ring, but they're shocked to find it on the hand of Stan's new girlfriend. While hosting Will's surrogate for the weekend, Will and Grace become the old folks they swore they'd never become.
Will ropes Dr. DiLorenzo into going on a fake date so he can spy on his surrogate. Grace struggles with popping her gender reveal balloon Karen is torn between celebrating her team's championship and helping Jack with his Broadway audition.
Will claims living with Grace is like Ricky living with Lucy. When Karen and Jack hear this, they each claim that they are the Lucy of the group. Grace, Karen and Jack each imagine themselves as Lucy, with Will as the Ricky to all of them.
Karen celebrates her baseball team's championship. Will and Grace go to an open house, which leads to a conversation about their future living arrangement. Jack has to decide if he wants to stay in the city to pursue his dreams.
Will is determined to not reminisce about his life in the city or his ex; Grace has false alarms of going into labor; Karen attempts to get closure with her ex-husband. Jack's dream of taking a bow on a Broadway stage becomes a very real possibility.