When Don Minu La Piana, the old head of the 'Ndrangheta, orders 5 tons of cocaine to assert his power over the criminal organization, the Lynwood family has to broke the deal. Unbeknownst to them, though, in Mexico a handful of soldiers led by Manuel Quinteras chases the heads of the Leyra drug cartel.
A large shipment of cocaine has a troubled journey from Monterrey, Mexico to Gioia Tauro, Italy. The sellers are the narcos brothers Enrique and Jacinto Leyra, who are aided in their criminal activities by Manuel Contreras and his group of corrupt soldiers; the buyer is Don Minu La Piana, a boss of the 'Ndrangheta, whose position is challenged by his grandson Stefano and the Curtiga family; the brokers in charge of the shipment are the Lynwoods, an American family from New Orleans owning a prestigious shipping company. The infighting within the 'Ndrangheta causes the shipment to be rerouted to Africa, and the delay has dramatic consequences for all the interested parties.