Jamie gets a lead on the chemist who manufactured the bacteria found in the wolf, and the trail leads her, Jackson, and Ben into the swamps to find the man. Meanwhile, Chloe, Mitch, and Abraham fly to Rio to investigate bat swarms and discover one of the reasons why the animals are attacking human beings.
Zoo is set amidst a wave of unhappy animal attacks sweeping across the planet. A young renegade scientist is thrust into a race to unlock the mystery behind this pandemic before time runs out for animals and humans alike.