The eight teams take off from their Pit Stop in Africa, first traveling to a slave-house where slaves were held until heading to the New World. There, a memorial to those slaves particularly touches Gus and has him appreciating the human aspect of The Amazing Race. One team in particular had no money to begin with because of their penalty in the previous leg so they had to ask the locals of Goree for money before leaving the island.

Next, the teams fly to Germany where they search for a clue along the remains of the Berlin Wall. After some teams have confusion about finding the clue, they travel to a statue of busted chains near a church that was partially destroyed in World War II. There, A Detour has teams choose between linking sausages or going to a brauhaus to search for their pictures on coasters and exchanging them for cups of beer at a brauhaus. Both choices were challenging and required high team work. Soon, the teams encounter a Roadblock in which one member must race a soapbox car down a mountain finishing before 37 seconds. The next clue instructed teams to find the next Pit Stop located at the Brandenburg Gate. On the way, one team remains in last place but another makes a costly mistake before the Roadblock resulting in a tense foot-race to the finish. In the end, one team member yells at his partner about losing causing some major stress while another is too late to check in and are eliminated.

A nun whose hands are red, swollen and cracked is sent to House. The nun believes it is stigmata, but House suspects an allergic reaction. He gives her some pills, which cause her to become unable to breathe. As her condition worsens, her fellow sisters pray for her while House and his team work to discover the cause of her illness while House has to wonder if he misadministered the illness.

While on an undercover operation as an escaped prisoner who is forced to stick to a convict that owns a key to an expensive ancient Iraqi sculpture, Tony mysteriously disappears. The GPS locator that Abby planted on him doesn't work anymore and the team must find Tony, because his life is in jeopardy.

Mosquitoes hit the town hard and only Hank seems unaffected. Lacey finally gets a chance to participate in a genuine Dog River activity by contributing to the town's less than impressive time capsule. And Oscar goes back to work at Corner Gas which irritates Wanda, puzzles Emma and sends Brent running to the Ruby, where Lacey's new serve-yourself coffee carafes prove troublesome.

The contestants are given an overwhelming surprise when they come face-to-face with their old, bigger, selves - cardboard cutouts as they apperaed the first day they arrived. The players run around a track with a weighted vest carrying the weight that each has lost so far. Ryan comes closest to his time from a previous run, winning himself immunity. At the weigh-in, Maurice and Lisa find themselves eligible for elimination, and when the other players vote, Ryan betrays his pinky promise with Lisa by being the swing vote for her ticket out of the house.

Jim tangles with a department store Santa after the two are involved in a parking lot fender bender. Unfortunately, Jim's kids witness the skirmish and are fearful Santa won't leave them any gifts for Christmas.

Lynn Echolls hires Keith to investigate a threatening letter sent to Aaron. He must track down the woman who sent the letter and stop her from coming to the Echolls Family's annual Christmas party.

Someone steals Weevil's winnings in a poker game with the 09ers, and he starts stealing stuff that belongs to them. They ask Veronica to help find out who stole the money so that they will get their stuff back.

Spinner hasn't talked to Jimmy since the shooting, and his part in it leaves him wracked with guilt. The more time Spinner spends with Jimmy, the more guilty Spinner feels - until he confesses to the part he played... . Spinner feels better, but only for a moment.

Dore Gold