Another houseguest is evicted from the compound.

In order to catch a bioweapons specialist, Michael and Fiona go undercover at a South American resort. In the meantime, Sam and Jesse corner Max's killer.

The designers are paired with students of Harlem School of the Arts. They have to create a piece of art, which also should inspire them for their next garment. Kenneth Cole is the guest judge.

The Degrassi students attend prom. Drew invites his ex-girlfriend, Bianca to the prom, and things are awkward with his current girlfriend Katie. Riley and Zane talk for the first time since their breakup, Riley tells Zane his mother accepts him. Clare talks to Jake about how their parents marring will affect their relationship, and he breaks up with her. Vince, the gang member comes to fight Drew, when that fails, a gun is pulled, and Adam, Drew's transgender step-brother, is shot in the shoulder. Miss Oh and Sav both find out via text message, as they have snuck away to Degrassi. Bianca decides to shoot Vince, but Drew talks her out of it. They call the police and Vince and his gang are arrested, The next day the heat between Miss Oh and Sav is still there.

Bender overclocks his processor and becomes a godly power of the universe.

Andy, Dov and Traci participate in an undercover training exercise which results in some unplanned situations and choices. Chris and Gail must determine if a young boy found tied up is the result of bullying.

Harvey's former mentor (Gary Cole) turns to his protégé when his office comes under investigation. Elsewhere, Mike and Louis try to settle a mogul's estate in the midst of family clashes; and Jenny worries that Mike is hiding something.

Just as Ryan finds happiness in his life, Wilfred begs him to sacrifice it for a larger purpose.

Building tools and technology and the possibility that they were influenced by aliens are explored. Included: a mountaintop fortress in Peru; and temples at Vijayanagar, India.

Louie waits at Grand Central Station to pick up his sister and niece for a visit. However, his sister surprises him by dumping the niece Amy on him and running off to catch a train to Philadelphia. Louie and Amy spend the night in New York together, visiting an indie rock club at her request, after which she asks to see Louie perform. After seeing her enamored with Godfrey's set, Louie attempts, unsuccessfully, to impress his niece by doing crowd work. After the set, Louie is surprised to see Godfrey spark up a lively conversation with the usually sullen teen. When they arrive back at the apartment, Louie receives a call from a Philadelphia hospital informing him that Amy's mother was found "acting irrationally" in a public fountain and that she is being held under observation. With Amy's father out of the picture, Louie volunteers to keep Amy until his sister is released.

With Mark working all the time, Randall feels neglected, so he decides that they should spend more time together to decide if they should stay roommates. And Grimes's Mummy returns from the dead, only to find fault with everything Grimes is doing.

Actress Julianna Margulies; comic Joe Wong; Lady Antebellum performs.

Heidi Klum, Kevin Smith, Fitz and the Tantrums

Trent plans a cruise for the NTSF team, but he's got ulterior motives to capture a terrorist rumored to be hiding out on the ship. Meanwhile, Piper brings her new fiancé along for the trip.

Kathy Griffin, Lynette Rice

The Brockman family find themselves having to some difficult decisions about work, video games and who should go to a family funeral. They end up leaving the vicar wishing none of them had attended.