Mary (guest-star Jessica Biel) makes a surprise visit home to deliver unexpected news to Eric and Annie. Meanwhile, Simon tells Cecilia (Ashlee Simpson) that he needs space. Also, Lucy and Kevin adjust to married life. Chandler breaks up with Roxanne after learning that she isn't comfortable with the idea of being a preacher's wife, while Roxanne seeks Kevin's advice on dealing with a dispirited Chandler. Also, the Camdens finally learn who's pregnant. Lastly, Eric ponders Simon's academic future and Annie prepares for a potentially tense dinner engagement.

Contestants try and face their fears as they battle it out to be crowned this week's winner.

Andy is concerned that Ephram needs more extracurricular activities to get into a top college, but Ephram is only focused on his Julliard audition, which has surprising results. Amy's lack of interest in college preparation alarms her mother more than her father. Bright's poor grades get him kicked off the football team, threatening the scholarship his father believes may be his only chance to get into a decent school. Meanwhile, Andy tries to help a cheerleader (guest-star Kristen Bell) with ruptured breast implants, who cares more about looking good than her own health.

Charlie's life is turned upside down when his brother and nephew move in with him.

Horatio investigates the murder of a model intentionally run down outside of a Miami hotel by a driver who fled the scene. When the evidence leads to a suspect, governmental red tape puts an unexpected twist on the proceedings. Horatio and Yelina begin to confront their feelings for one another.

Welcome to the Montecito Hotel & Casino, one of Las Vegas' finest establishments. This is also the worst day of Danny McCoy's life. Danny is an ex-marine who works for Ed Deline and the Montecito Surveillance Team. Danny's day starts off when Ed catches him in bed with his daughter, Delinda. Things only get worse for Danny as he must handle a drugged up bum who is on a winning streak, find one of the casino's high rollers who has disappeared, and figure out how the big winner on the blackjack table is cheating. Just another day at the Montecito...