Matt, Mary and Lucy make plans to get away from the family for Thanksgiving, but when Eric's sister Julie comes to spend the holiday's with them, plans are changed. After the family finds out about Julie's dangerous secret: her drinking problem- everyone decides it would be better to stay home. Eric decides to help his little sister overcome her problem at home rather than seek professional help- whether she wants it or not. Although, Annie is not comfortable with the situation and is only concerned that the children stay safe after an unfortunate altercation between Julie and Simon earlier.

Cadet Nog returns to Deep Space Nine to begin his field training. To keep him company, Jake moves in with him. Meanwhile, Quark has been accused of a high security crime and is being taken by Odo to the grand jury hearing.

Trapped in the body of Callisto, Xena must help a mortal Ares recover his sword and restore him as the god of war. If she doesn't mortals will not be able to control their anger and she'll never recover her own body.

This program reveals some of the billions of practically invisible organisms that live on, in, and around us.

In an attempt to divert Kay's attention from FYI Murphy suggests that Kay produce a new afternoon talk show that she also convinces Stan that he can host. Frank even gets to play the saxophone in the house band. The premiere show starts out real bad and guest Tom Hanks escapes. Murphy becomes the replacement guest.

This week's guests are Andy McCluskey, David McAlmont, Martin Chambers and Bob Mortimer.