Quinn and Rembrandt head down to Mexico to blow off a little steam. Getting back into the United States turns out to be a bit of a problem when they get mixed up in an illegal snake trade and find themselves stuck in the middle of a jungle, surrounded by deadly snakes and the tobacco cartel. Meanwhile, Wade and Maggie run into problems of their own while they search for the other Sliders.

Frank and Peter investigate a series of Satanic murders and get caught in a battle between good and evil.

A bored Sabrina gets more than she bargained for when Hilda offers her a "can of worms" spell to spice up her daily grind, which is transformed into a melodramatic soap opera. When a mysterious one-eyed janitor accidentally beans Harvey with a ladder, Sabrina's sweetheart wakes up with amnesia, and a dastardly Libby seizes the chance to steal him, convincing him that he has agreed to kiss her publicly at the climax of the school fashion show; Libby also steals the diamond ring Mr. Poole is about to offer the buxom school nurse and plants it on Sabrina, who must enlist her aunt's help to demonstrate her innocence before the spells runs its narrative course. A chastened Sabrina joins Salem in the less hazardous hobby of watching floating lint.