Stardate 51244.3 An unknown and unseen force is causing medical changes in Voyager's crew. Janeway has terrible headaches, Chakotay, Neelix and others show signs of devastating changes to their DNA.

Even though his program becomes deactivated, the Doctor reaches out to Seven of Nine for her help in finding out what is going on. He modifies her implants to allow her to see those causing the medical changes, but she must remain quiet about what she sees, as know one would likely believe her.

It's now up to Seven of Nine to save Voyager from this unseen attack, before the crew suffers irreparable bodily damage.

Dick turns out to be a scaredy cat when faced with the prospect of a physical exam. Meanwhile, Sally and Tommy house-sit at Albright's house on Halloween night - that's bad news for neighborhood trick-or-treaters - and Harry stays home alone, except for some very weird noises coming from the basement.

When Greg's competitive nature becomes destructive, Dharma exposes him to yoga, hoping to lower his stress level. After two classes, however, they both realize Greg's life is out of control when he gets into a macho "I can do this" contest with Pete and pulls a groin muscle. Meanwhile, Larry goes to Edward with a scheme to mass-market videos of Dharma's yoga instruction.

An unenthusiastic Noah discusses his investment portfolio with a business manager. He covers by telling Valerie that the man was a boat owner. Val accepts an invitation to a ball from Cooper and tries to keep Noah away. He shows up to surprise her; both men get mad and dump Valerie. The building owner evicts David for failing to pay the club's rent. He steals a check from Donna and forges her name. Donna takes a job for a woman who she believes is the widow of a major fashion designer. The woman seeks her help in retaining a psychic to ask her dead husband about some hidden jewels. David angers Donna by skipping the ball. Steve escorts Carly to the event, although they have to leave early to tend to an ailing Zach. Kelly fears that she and Brandon are in a rut, so they do it at every conceivable opportunity.

The Mayor agrees to a mock election with a popular disc jockey. Meanwhile, the women in the office compete for the affections of the water delivery man.

Frank can't stop telling the story about him punching the paparazzi. Murphy returns to work the day after her surgery and she looks like hell and is very disoriented. Corky takes her home at offers to stay with her for a couple of days. Murphy becomes so dependent upon Corky that Corky hasn't got the time to take care of her own problems, such as her failing marriage to Miles.

A discrepancy concerning the time of death of a drive-by shooting victim leads McCoy and Ross to initiate prosecutions against both the shooter and the doctor who harvested her organs as transplant donations.

The first Halloween episode starts off with the failure of the Mir Space Station, which crashes right on Kenny. An ambulance comes and takes his body off to the morgue. The boys start to brag about their Halloween costumes. At the morgue, a freak accident involving a bottle of Worcestershire occurs, and next thing you know Kenny is a member of the undead. Kenny breaks free and wanders off into the night.

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