Simon is kidnapped by some villagers who desperately need a doctor. Back at Serenity, Book is severely injured and needs medical help. Unable to find Simon, Serenity takes off without him to find medical help... in an Alliance facility.

Sabrina meets the handsome owner (Austin Peck) of an art gallery, and decides to make a date with him instead of going out with her friends. But she has a change of heart when she realizes he may want to add her to his collection of exotic creatures.

When a young boy Wesley and his mother approach John Doe claiming that sperm bank records indicate he is the boy's father, John is pulled into a mystery as he tries to track down the list of donors and finds two of them dead, their brains removed.

When the decomposing body of sexually molested five-year-old girl is discovered, Detectives Benson and Stabler's investigation leads them to the painful reality that they are searching for a serial pedophile as they race to save the life of his latest victim. As the mother of the missing girl frantically awaits news of her daughter's whereabouts, she must reconcile the fact that her own recent bout with addiction may have played a part in her daughter's fate.

While taking a trip on a Old West-style train, Jack is stalked by a bounty hunter, Ezekial Clench. He manages to defeat him but unwittingly falls prey to Ezekial's ex-wife Josephine.

A village is having trouble with a group and their Dodrio and need help.

Wanda receives a clue from one of Magneto's minions, Pyro, directing her to a ski resort. Meanwhile, Kurt is meeting Amanda's parents for the first time, and the Toad believes he can use Kurt's holo-inducer to disguise himself and win Wanda's love.

Lara faces judgement day in the appeal court; a suspected overdose patient forces Roxy to confront ghosts from her past.