Owen Wilson hosts with musical guest Kacey Musgraves.

Kim Kardashian West hosts with musical guest Halsey.

Rami Malek hosts with musical guest Young Thug.

Jason Sudeikis hosts with musical guest Brandi Carlile.

Kieran Culkin hosts with musical guest Ed Sheeran.

Jonathan Majors hosts with musical guest Taylor Swift.

Simu Liu hosts with musical guest Saweetie.

Billie Eilish hosts and performs as the musical artist. Kate McKinnon returns presenting the CDC Players.

Actor and People's sexiest man of 2021 hosts. Musical artist Charlie XCX performs.

Sketches include: NBA on TNT, Urkel, Formal Emporium, Eric Adams is from New York City, Weekend Update, The Sound of Music 2.0, Sappho Lecture, Longhorn Steakhouse

Sketches include: MacGruber, Kid Klash, Cinema Classics, Threesome, Weekend Update, The Return of Clancy T. Bachleratt and Jackie Snad

Sketches include: Tenant's Meeting, "Now I'm Up", Badminster Dog Show, Can't Get Hard, Beauty and the Masturbates, A Please Don't Destroy Video: Connor, Blowing Yourself, Jeremiah the Temp

John Mulaney hosts Saturday Night Live on February 26, 2022 with musical guest LCD Soundsystem.

Oscar Isaac hosts Saturday Night Live on March 5th, 2022 with musical guest Charli XCX.

Zoe Kravitz hosts Saturday Night Live on March 12th, 2022 with musical guest Rosalia.

Jerrod Carmichael hosts Saturday Night Live on April 2, 2022 with musical guestballoonna.

Jake Gyllenhaal hosts Saturday Night Live on April 9, 2022 with musical guest Camila Cabello.

Lizzo hosts and performs as musical guest on Saturday Night Live on April 16, 2022.

Benedict Cumberbatch hosts Saturday Night Live on May 7, 2022 with musical guest Arcade Fire.

Selena Gomez hosts Saturday Night Live on May 14th, 2022 with musical guest Post Malone.

Natasha Lyonne hosts Saturday Night Live on May 21th, 2022 with musical guest Japanese Breakfast.