Caroline Rhea returns to welcome fourteen new players to The Biggest Loser and to host them at their stay at the new ranch. After being faced with a room of tempting food, the players discover a twist in the game - this time it's men vs. women! The women, who will always wear Red, will be trained by Jillian Michaels, while the Blue team, the men, will be put to the test by Bob Harper. Later, the new teams compete in the first challenge of the season - a competition that takes place in a jet so that the contestants can experience what it feels like to weigh nothing! At the end of this 90-minute episode, one of the hopefuls will be voted off of their team. Who will survive the battle of the sexes Biggest Loser style?

The contestants' diets are put to the test when they are told that if they eat some high-calorie treats, they will be given a letter from home. Who will be able to resist the temptation? Plus, who will win the next challenge, which deals with balance, and who will be voted off of their team?

Twelve contestants remain, as they continue to endure the pain from their injuries and the disputes from their trainers. They'll have to decide whether to continue on with the next physical challenge and resist the food temptations that continue to tempt them. Can they do it?

When the teams get a chance to go to Las Vegas, they'll have to endure some very tempting temptations. They will have to make some very tough decisions while they're there. Will they be able to resist, or will they lose it all for some cash?

As the teams continue to lose teammates, one team begins to lose their confidence. So, their trainer brings in a special visitor from the past to talk to them and help them regain their confidence once again. But will this be enough to get the team back on track, or will the team continue to fall apart, despite their trainer's efforts?

Because of the Blue Team's subpar performance on previous weekly challenges, the team decides to push themselves during workouts, as well as try harder to get along with each other. Meanwhile, Jillian pushes her team to go on their most dangerous workout yet. Can they handle it?

As eight contestants remain, everything changes with twists at every corner. The teams are no more, contestants are forced to work with their enemies, and even the weigh-in will have a special twist this time around. All this leads up to the most shocking elimination yet. Who will it be?

In order to participate in a professional photo shoot, all seven remaining contestants receive a Beverly Hills-style make-over. Afterwards, a special surprise awaits the seven contestants at the pedicab race when their family members arrive for a surprise visit, as they become the cargo for the race. The winner will not only receive immunity for the week, but he/she will also get to spend an evening with their family.

Caroline informs the remaining six contestants that the duos are gone from here on out. Now, they will all be competing against each other by themselves. Aside from this change in the game, one contestant will shock everyone with their new look. Meanwhile, two other contestants will end up having a fight between each other.

The guys open up and share their dreams before all five remaining contestants take on a nightmarish endurance challenge. By wrapping their arms and legs around a one-foot diameter tube suspended before them above a swimming pool, they hang on as long as they can. The last one to fall makes a splash as the winner of this event.

During the last episode taped at the ranch, the final four contestants discover how far they have come in terms of weight loss and exercise by doing the same workout from their first day at the ranch. For their challenge, they have enough quarters to equal the weight they have lost since the first episode placed on their backs. Weighted with coins, they must scale the side of the building, and then make a second trip up the side minus the extra weight. The contestant with the most improved time between the climbs wins, and even gets to keep their quarters.

After weeks of training and careful eating, it comes down to choosing "The Biggest Loser" in this special two-hour, live season finale. Only three contestants remain in the contest to see who has the biggest percentage of weight-loss. The winner will be chosen during the live portion of the telecast.

* Two-hour episode