Marty Weaver just wants the best for his wife, Debbie, and their three kids. That's why he's moving them to Hidden Hills, New Jersey, a gated community complete with its own golf course. Marty is certain that their new home will be a dream come true. And then, they meet the neighbors... aliens from the planet Zabvron - and the Weavers are the first humans they've ever met.
After convincing the Bird-Kersees to let their kids try "human" school, the Weavers take them on their first excursion outside Hidden Hills - shopping for back-to-school clothes at the mall. They survived the trip to Earth, but will the mall be too much? Meanwhile, Debbie and Jackie have doubts about each other's true intentions.
Marty and Debbie decide to make plans with their human friends after Larry and Jackie have become too entangled in their daily lives. The Weavers do their best to un-invite the Bird-Kersees, explaining they're afraid their friends won't be accepting of the aliens. But that doesn't stop Larry and Jackie from crashing Marty's' poker night and Debbie's girls' night on the town - with hilarious results.
Marty and Debbie prepare the Bird-Kersees for their kids' first day of human school. They're especially worried that little Dick Butkus will get picked on, but their anti-bullying advice backfires in ways they never anticipated. Meanwhile, Larry and Jackie are getting tired of the Weavers' endless parenting tips.
Since arriving on Earth, the aliens - led by the Bird-Kersees - have viewed Halloween as a threat and have set up a barrier at the gates of Hidden Hills to prevent children dressed in costumes from entering the community. The Weavers, on the other hand, are excited about their first Halloween in the suburbs and want to open the gates of the community to celebrate. They do their best to explain the ritual of trick-or-treating to the aliens. Meanwhile, Marty and Debbie's fears are realized when Amber, Max and Abby reject their family costume plans.
Jackie Joyner-Kersee tries her best to help as Debbie whips herself into a frenzy planning the perfect birthday for little Abby. Meanwhile Larry shadows Lenny at work for a day; and a smitten Reggie Jackson tries to find the perfect gift for Amber (even if it isn't her birthday).
Marty and Debbie find out all the facts of alien love when Zabvronian mating season coincides with their wedding anniversary. Debbie longs for a little more romance in her marriage after she learns about the more cerebral Zabvronian way, while Jackie Joyner-Kersee is fascinated by humans' more physical approach. Meanwhile, a handsome jock invites Amber to a make-out party and she decides to go, with Reggie Jackson tagging along.
Debbie wants her family's first Thanksgiving at their new home to be different from Thanksgivings past, so she convinces Marty to un-invite his parents and decides to invite Larry, Jackie, Reggie and Dick over for the holiday instead. Unfortunately, despite his promise to Debbie, Marty caves to parental pressure and confirms his mother and father will be on hand for Turkey Day. Meanwhile, after learning the meaning of the holiday, Dick secretly invites Jackie's estranged sisters, Venus and Serena, to make an appearance. Thanksgiving Day is anything but normal with the crazy alien neighbors, alien and human in-laws, and the Weavers all under one roof.
Marty and Debbie dislike the kids' entitled attitude towards Christmas and decide to return their gifts and use the money for a family vacation; when the Weavers realize the aliens already opened all the presents, Larry Bird must save Christmas.
When Hidden Hills' beloved gardener, Juan, unexpectedly dies, the aliens are forced to deal with something totally foreign to them. Debbie and Marty struggle to explain that passing is something that comes to all humans, eventually, but Larry Bird is determined to find a way to solve that little problem, starting with the recently departed Juan.
Larry Bird helps Debbie deal with PTA politics and its officious president, Linda (Nora Dunn); Jackie's competitive nature kicks in when she helps Marty coach soccer.
When the whole Weaver family comes down with a cold, the Bird-Kersees - especially Larry - are terrified and confused.
Debbie decides to sign herself and Marty up as chaperones to the high school dance as a way of reliving her own high school memories. The Bird-Kersees, of course, tag along as fascinated observers.
When the Weavers and Bird-Kersees compete for membership in a brand-new, exclusive country club, they're forced to confront issues of class and race. Marty and Debbie become so obsessed with getting into the club that they blow off their alien neighbors and bring the kids to an open house for prospective members. When Larry and Jackie show up at the club unexpectedly, the results for both families are not what anyone had expected.
Debbie's relationship advice to Reggie Jackson about nerdy new girlfriend Giselle backfires badly, making things even more difficult for Jackie and Larry, who are having a hard time dealing with the fact Reggie even has a love life. Meanwhile, Amber resists Debbie's attempts to talk about her new boyfriend, handsome but dim jock Jeremy.
After Debbie fears she's lost her looks and Jackie discovers that on Earth she's considered a "10" (back home Larry Bird was the pretty one), they end up in Hell (literally), a hip new club, hoping to feel a little more like desirable women and a little less like moms, in this episode that airs as part of ABC's Wednesday comedy Valentine's Day salute. Meanwhile, Marty and a deflated Larry Bird look to Amber to help them makeover their drab appearances.
Max makes it into the final round of the school spelling bee. When he finds himself going head to head with Dick Butkus, Larry and Reggie, who've become obsessed with winning an Oscar, decide to videotape the bee - and the competition between Max and Dick - hoping to take home the award for Best Documentary.
The Weavers and the Bird-Kersees unplug for a weekend of camping in the great outdoors, as Marty tries to prove he's a "manly man" like his dad, Dominick. Debbie and Jackie work secretly behind the scenes to make the trip a success for an oblivious Marty, but all bets are off when both families have a close encounter of the animal kind.
The Bird-Kersees take Marty up on his offer to teach them how to drive - after all, they piloted a spaceship to Earth, how hard can driving be? Meanwhile, Amber refuses to let Marty teach her, a decision she soon regrets when she ends up with unconventional Driver's Ed teacher Ms. Porsche.
Increasingly comfortable exploring the world outside of their gated community, the Bird-Kersees ignore the Weavers' concerns and decide to go to into the city to see a Broadway show. Inspired by the experience, Larry decides to put on a musical of his own, which goes well until Dick literally missteps. Instead of going to Marty and Debbie for help (as they have done many times before), the Bird-Kersees risk exposing their true identities when they call 9-1-1.
Debbie is thrilled when a tough-minded businesswoman (guest star Bethenny Frankel as Jill) offers her a chance to revitalize her purse business. Jackie jumps in to help, but her negotiating skills work a little too well, and they're soon in way over their heads trying to produce an impossible number of purses.
The Weavers take the Bird-Kersees to Atlantic City, where Marty learns that Larry Bird not only counts cards, he can see through them, and Jackie admits that she's always wanted a human wedding. Meanwhile, Dick Butkus, in charge back home, gets an ominous call from his Grandpa. Is it time for the Neighbors to return to Zabvron?