This season of the Ultimate Fighter features heavyweights including superstar street fighter Kimbo Slice. Coaches Rampage Jackson and Rashad Evans continually argue before picking teams. The first preliminary fight takes place.

Rampage scrambles to teach Kimbo new skills, while Team Rashad's Roy Nelson is deemed "uncoachable". Team Rampage picks the next matchup, pitting size against skills.

Street-fighter Kimbo Slice races to learn all he can before he takes on former IFL champion Roy "Big Country" Nelson. And ex-NFL giant Marcus Jones causes trouble for Rampage.

A fighter keels over at the house, giving Kimbo hope for a comeback. A member of Team Rashad spills the beans on their fight strategy. And, two more heavyweights do battle as Team Rashad tries to extend its winning streak.

Zak Jensen faces mockery at the house and problems in training. Matt Mitrione tests Rashad's patience with an on-again/off-again shoulder issue. Rampage looks to break his losing streak in the fifth preliminary fight.

Rampage's hazing of Darrill Schoonover reaches a boiling point. After relentless teasing at the house, the fighters bet on which day Zak Jensen will finally snap. An injury puts a fighter's future in doubt.

Rampage and Rashad nearly come to blows. Matt Mitrione continues to cause problems for his team by betraying one fighter and then lashing out at another. The 7th preliminary fight takes place.

Matt Mitrione and Scott Junk return from their fight, battered and bruised. In the last preliminary fight, Jones faces Mike Wessel. The quarterfinal matchups are announced.

Mitrione wavers on whether he can fight, sparking speculation that Kimbo will return to the Octagon. Justin Wren and Roy Nelson square off in the first quarterfinal fight.

Questions continue about whether Matt Mitrione will fight, prompting a visit from Dana. Kimbo battles an injury with hopes of returning as a replacement. Teammates Brendan Schaub and Jon Madsen face off in the second quarterfinal fight.

.Kimbo Slice makes a surprising decision to Dana, Scott Junk has a shocking announcement from his doctor. The quarterfinals and semi-finals with fights that include: Matt Mitrione vs. James McSweeney, and Marcus Jones vs. Darrill Schoonover.

Scheduled fights include Matt Mitrione vs. Marcus Jones, Kimbo Slice vs.Houston Alexander, Frank Edgar vs. Matt Veach, Darrill Schoonover vs. James McSweeney, Jon Madsen vs. Justin Wren, Brian Stan fights Rodney Wallace, John Howard takes on Dennis Hallman, Mark Bocek against John Brammer, and in the finale of the Heavyweights Roy Nelson looks to beat Brendan Schaub.

Season 10 ends with a final bout in Las Vegas to determine the recipient of a six-figure UFC contract. Also featured on the card Light Heavyweight bout between Matt Hamill and Jon Jones.