While on a biosurvey mission in the Gamma Quadrant, Doctor Bashir, Commander Dax, and Major Kira receive a distress signal on their Runabout from a planet. Arriving, Bashir and Dax beam down to a world of people slowly dying from an illness that begins at birth and eventually kills them, a virus given to them by the Dominion for defying them. The Federation members stay in order to help find a cure for the planet.

Chakotay receives an urgent subspace message from Seska. She tells him that Culluh plans to remove her and Chakotay's new born child from her. Chakotay is conflicted as to what he should do. Should he ask the crew to fly into harms way to save his son? Should he even trust Seska to be telling the truth?

Things take a sudden turn when one of Culluh's crew shows up and tells them that Cullah has killed Seska, and has taken the baby to a certain world to be raised. As Voyager heads off to rescue the baby, they find they are under constant attacks by the Kazon.

Just when things begin going their way, the Kazon spring their own surprise on Voyager. The Kazon now have the upper hand.

The mansion's for sale and everybody's in the fast lane...except Will, who's stuck on life's soft shoulder.

The Banks move out. The Jeffersons are about to move in. And Will turns out the lights.

The unemployed staff members decide it would be a slap in the face to the network if they helped Jim and his team out. Miller wants to move into Murphy's office. Miles fills Lansing in on the state of things. Lansing offers advice to Miles, which he declines. Lansing concedes, FYI is back, complete with Jim; the network is going to let them run the tobacco story. Charles Kuralt takes over Jim's responsibilities at ICN. Impressed with Miles' hardball tactics, Lansing offers him a big job in New York City and he accepts.