Lois and Hal are spending the weekend at a family wedding, leaving Francis - home for a visit - in charge. When Malcolm overhears them discussing whether Francis has spent long enough at the military academy, he enlists his brothers in a scheme to get Francis home by preventing any of the usual disasters. But three of Francis's dude buddies turn up to party and trash the house, and while frantically cleaning up Malcolm gets a serious head injury that necessitates the usual trip to the emergency ward. How to prevent Mom and Dad from finding out? Enter Caroline, who has begged Malcolm to look on her not just as his teacher but also as his "friend" - a declaration that costs her $400 in medical bills. Meanwhile, Hal and Lois discover that his family has a new nickname for her: "Lois Common Denominator". Her humiliation provokes Hal to declare his devotion to her - and the snooty bride and groom discover that their honeymoon car is already being put to use... . Home again, Mom and Dad a

Springfield is going to give an award to the town's oldest man, but when that guy dies, Mr. Burns gets the award instead. He decides to get a check-up at the Mayo Clinic with Smithers. When he leaves, he leaves the Simpson family as caretakers of his mansion. Homer starts living the life of a billionaire, but of course, he is highly destructive. He wants to throw a box social at the mansion for all his friends, but Marge pleads with him not to do it. He tries to get a few kegs for it from Moe, but local law prohibits the sale of alcohol before 2 PM. He cannot wait, so he takes Burns' yacht out to international waters, where no laws apply. Pirates see them whooping it up aboard the yacht and they rob them, put them into nets and then try to drown them. Fortunately they just float in the net back home. Meanwhile at the Mayo Clinic, Mr. Burns is told he has every disease known and unknown to man, it's just that they are all existing and trying to get through the door together in something the doctor's call "Three Stooges Syndrome". The doctors do warn him that a stiff breeze could kill him. Back in Springfield, Burns is not too upset about losing his yacht and the Simpson family returns to living their "simple" life.

Mulder and Scully doubt that it was a case of divine intervention, when several deaths seem to be linked to snakes which are killing the unrighteous.

Tony plays both ends against the middle in a construction dispute, while Pussy has a revealing meeting with an FBI agent.
Livia becomes suspicious of Janice as she starts to get cozy.
Junior is released from jail, but finds himself working on a tight leash under Tony's thumb.

Gutiérrez arrives at the Ecomoda beaten, scratched and furious, and asks Bertha and Fredy to resign. The barracks asks Armando for help and he confronts Gutiérrez. Mario comes up with a new sales strategy to save the company.