Chip must choose from members of 'N Sync fighting amongst themselves during a video shoot (Wayne), an insult comic reincarnated as a ravenous blood-sucking leech (Colin), and a bride going through progressively worsening wedding day with her husband, Colin (Ryan), in "Let's Make a Date"; Chip and Wayne sing a "Duet" to Anna the sign language interpreter as Rod Stewart and Tina Turner; a Dracula "Scene to Rap"; Chip hosts "Party Quirks", with an attendee of a keg party from sober to passed out in 30 seconds (Wayne), an overly dramatic private investigator finding ridiculous clues to a murder (Colin), and a panicking, trapped bird who keeps mistaking cameras for open windows (Ryan); a "Doo-Wop" song by Wayne, Ryan, and Chip about Cheryl, who died in a tragic knitting accident.
Colin wins, so it's Wayne and Chip vs. Drew and Ryan in "Props".

Phoebe suspects that Rachel is pregnant, so she covers for her at Monica and Chandler's wedding reception.

Grissom and crew are called in after high roller Tony Braun, a known drug addict, is found dead in his house by a gardener. Since drug paraphernalia is discovered near his body and it is also determined that he had recently inhaled heroin, the cause of death is at first thought to be an overdose. But further examination of the corpse reveals that Braun had been restrained at some point with duct tape, leading Grissom to believe that the victim was forced to ingest lethal amounts of heroin and, perhaps, other drugs.

Will returns from vacation to discover that Grace's romantic relationship with neighbor Nathan is humming along -- but Nathan feels neglected when Will and Grace resume their chummy friendship, complete with their own private language and code. Meanwhile, Jack proudly takes his newfound son shopping for school at Barney's while Rosario and Karen each cruise the merchandise looking for the perfect anniversary gift.

Season Premiere. Three weeks after the death of Derek Fossen, Greene faces interrogation at an M&M conference. However, Corday is the only one to suspect something wrong. Meanwhile, Carter's parents return to town for his grandfather's funeral, which Abby briefly attends. Abby has decisions to make; Luka wants her to move in with him. Weaver returns from an impromptu vacation, worried that Romano has outed her to the staff. Chen is the new chief resident. Benton deals with Cleo's meds and Jackie's problems adjusting to life after Jesse's death. The ER is filled with patients after a brawl at a talk show taping. Legaspi got a job in San Francisco.

Tonight, rock band Tenacious D.