In Weird Newscasters, Colin is anchor to co-anchor Greg (German insult comic), sportscaster Wayne (girl scout selling cookies who's possessed by the devil) , and weatherman Ryan (old man who takes an extremely short-acting rejuvenation pill). Ryan is Doctor Frankenstein to Colin's Igor in Whose Line. Wayne and Greg are a tourist and his guide on a safari in Action Replay, Colin and Ryan act out the replay. Scenes From a Hat includes "Versions of Hell other than eternal flames", "Famous film scenes as performed by cartoon characters", "If morning show hosts acted like most people do in the morning", "What members of the Whose Line cast say to their therapists", and "Announcements that tend to ruin parties". Drew joins Wayne, Colin, and Ryan for the Hockey Player Hoedown.

After 60 years of looking, two old ghosts from Leo's past finally catch up to him, and demand revenge for his perceived slights against them. Unfortunately, it's his wife Piper that may end up paying the ultimate price.

In a surprising turn of events, Rotu loses both challenges, and officially, John becomes a leader for his tribe. Rob, however, sees through this, and schemes to get John ousted, with help from Sean, Vecepia and Gabe. In the end, everyone votes for Gabe, leaving not only himself surprised, but the viewers as well.

Monica regrets her request to supplant Ross as the designated toast-giver at their parent's 35th wedding anniversary. Phoebe's latest boyfriend drives everyone at the party crazy with his upbeat optimism.

A bus carrying 23 passengers from Los Angeles to Las Vegas crashes less than 40 miles from its destination, killing nine people. Before he dies, the driver recalls that, moments before the wreck, the steering wheel began vibrating like a jackhammer in his hands, making it impossible for him to control the speeding vehicle. When the bus finally did come to a stop, it was on its right side on top of a sports car that was following it. At the scene, the CSIs discover that a recent parolee was on the bus, but is now unaccounted for---and that there's evidence of foul play.

An excited Will presents his newly reconciled parents with a romantic cruise on their anniversary -- but his idealistic plans are scuttled when he learns that each is hiding a secret. Meanwhile, due to Karen's phobia about an elevator, she and Jack huff and puff their way up dozens of floors to the skytop restaurant while hefting the prized anniversary cake.

Corday, still living in the hotel, is avoiding Mark, until Ella says her first words. Elizabeth pressures Susan to tell her what her husband is hiding, and figures out her husband's fate. Romano advises her to return to Mark for the little time he has left. Chen treats a man too traumatized to speak. Mark tells the staff about his prognosis. Weaver worries about Sandy Lopez as she is reported missing in a fire. Weaver tracks her down at a bar, and the two make out. Stabbings on a college campus bring girls to the ER.

Fran starts spending time with a new-age friend to try and wind down while Bernard and Manny are having another fight. Bernard believes Manny is a psychopath and sends him to a therapist, where he unlocks a confidence he never knew he had.