Asher targets Louis but Cully saves the day.

Resulting from the showdown in the murder room, Brenda finds herself taking some involuntary time off. When she is asked to help a friend solve a murder that is linked to a terrorist group, Brenda works to find the killer and still keep it under wraps. Meanwhile, Commander Taylor jumps at the chance to break apart the PHD while Brenda is away.

Glad to be back with her team, Brenda focuses on finding a terrorist-linked suspect. Working with the CIA, who also wants their hands on this suspect, Brenda realizes that she was given false information, and wonders if she's been set up.To prevent herself and the PHD from falling prey to a sinister plan, Brenda must untangle a web of lies to determine who she can trust - before it's too late.

Peter is in police custody after being mistakenly arrested in Odessa, forcing Nathan to take time out of his Congressional campaign. Claire deals with the implications of telling her father the truth. Matt and Audrey pursue a new lead in the hunt for Sylar unaware that the killer has been captured by Mr. Bennet. Hiro and Ando arrive in Odessa, too late to "save the cheerleader." After Niki learns of Jessica's recent actions, she must make a difficult decision to keep her family safe and so she decides to get herself arrested. Mohinder takes fresh steps down his newly-chosen path by coming back to New York and continuing his fathers research. Isaac's painting of the exploding man comes into context with major consequences for the future of a certain hero, just as an even more mysterious painting is unveiled.

OCC suits up, and lays siege to their latest project, a dragon-rider bike inspired by the movie Eragon; Mikey takes on a crusade of his own and organizes a jousting tournament uniquely OCC.

With Christmas nearing, as well as the annual holiday Studio 60 episode, Matt sets himself on a personal mission to spread holiday cheer at the studio. Meanwhile, Danny is forced to confront his true feelings for Jordan.

Every begins to take the first steps in moving forward in their lives. Nicole tries to help Deena out with her cupcake business, but things turn interesting when Deena meets a rich client, who seems to be smitten by her. Dave tries to help Brian, who is trying to find ways to make Bridget interested in him. Dave tells him to go to a speed dating thing. He says to bring Bridget along so she could see the other jerks and then Brian would look better to her. Adam and Heather start to rethink getting married.

Pool hopes a water stain in the store that seemingly resembles Jesus will attract customers and boost slumping sales. Meanwhile, emotions are raw when the store freezer breaks down, threatening the meat inventory; and Carl tries to be a proper father to his son.

While they are on there way to the Battle Pyramid, Ash and the gang decide to stop at the Pewter Gym and see Brocks Family. When they finally arrive to there suprise, the Pewter City Gym has been made over with a different scenery before. As even more of a shock Brock learns that his Onix has evolved into a Steelix!

After that a Delibird, actually thinking that Jessie and James were Butch and Cassidy, gives Jessie and James a Charizard and Aggron. And now they are trying to take over the gym!

Abra is trying to cover his tracks over the kidney transplant, but Dan makes a discovery which jeopardizes Abra's career even more. Dan suspects that Jac wound up his ex. Connie reveals the father of the baby, shocking Sam while Mark drowns his sorrows.