Toby, thinking that there's something going on with Bartlet, connects the dots and figures out that the President has multiple sclerosis. Toby is the 17th person to find out about the President's ailment and quickly becomes the second person -- the first being Abbey -- to forcefully challenge him on the political and legal ramifications of hiding his disease. Meanwhile, Bartlet decide whether or not to order a heightened security alert for airports when a terrorist is caught at the U.S. border carrying explosives. Elsewhere, Sam and Josh try to add one-liners to the President's upcoming speech while Sam and Ainsley argue over equal rights for women.

Briscoe and Green investigate a couple murdered in their apartment, which leads them to the wife of a major in the U.S. army who is involved in anti-drug activities in Colombia, leaving McCoy with the awkward job of getting her to testify.

Tonight, comedian D.L. Hughley.