The residents of Wisteria Lane are stunned to discover that Paul Young is out of prison and back in the neighborhood with an enigmatic new wife and seemingly dark motives. Meanwhile, while Paul is renting Susan's home, she, Mike and MJ are living in an apartment on limited funds. But Susan sees a glimmer of hope in getting her life back on the Lane when she's offered an unorthodox job by her apartment manager, Maxine; Lynette's rich and successful college friend, Renee, pays an unexpected visit to the Scavo household; Gabrielle and Carlos find themselves keeping secrets from one another; and Bree, newly single and needing a fresh start after selling her business, finds herself tempted by Keith Austin - the handsome, young handyman she's hired to update her house.

After Renee begins spending a lot of time with Tom, an angry Lynette feels she's trying to sabotage their marriage; Bree fires Keith without warning when she suddenly finds herself falling for him; Susan is wracked with guilt about lying to Mike about her new, risque side job; Gabrielle rushes to the hospital after learning that Bree accidentally hit Juanita with the car; and Paul introduces the women of Wisteria Lane to his new wife.

Susan is less than pleased when she finds out that some her best and sexiest internet show moves are being copied by a competitor, and Gabrielle hires a private detective to look into an important matter, unbeknownst to Carlos. Meanwhile, Lynette is stunned when Tom's doctor prescribes him a rather unorthodox remedy for his depression, and Renee invites a reluctant Bree to go clubbing with her in order to engage in some local man-hunting.

Susan is horrified when she discovers that she has become the face of the provocative internet company she's been secretly working for, and is now the cover model for their outdoor billboard ads. Gabrielle tells her coveted secret to the ladies, and Renee finds out that Bree is a grandmother and uses it to her advantage in an attempt to steal Keith away and have him for herself.

Susan's days as a sexy internet sensation may be coming to an end after she angers an important client and incurs the wrath of her boss, Maxine. Meanwhile, Renee and Gabrielle are headed for a smackdown after each of them reveals an intimate secret about the other to the wrong people, and Bree finds herself exhausted by younger lover Keith's sexual stamina.

As Halloween approaches, Susan is forced to reveal her secret, sexy internet side job to a shocked Mike; Juanita becomes suspicious of Gabrielle's sudden interest in Grace; Lynette becomes concerned about Tom's mother's memory lapses; Bree learns a secret about Keith; and Paul is encouraged to take wife Beth out on a date in order to light a spark in their unromantic relationship.

Susan begrudgingly accepts Lynette's offer to be baby Paige's nanny; Bree is embarrassed to tell Keith that she's beginning to go through menopause; Renee makes a tempting job proposition to Lynette; Gabrielle fears that Bob is trying to seduce Carlos after the two strike up a friendship; and Beth begins to question Paul's motives on the lane.

Thanksgiving on Wisteria Lane finds Gabrielle and Carlos hosting Carmen, Hector and Grace to a bountiful feast. But the Solis's discover some surprising news about the Sanchez's that could threaten their time with Grace.

Gabrielle desperately tries to figure out a way to keep Grace in her life, and Keith plans a very special dinner with Bree. Meanwhile, Tom is angry at Lynette for not disclosing his special attributes to the other ladies, and Renee tells Susan a deep, dark secret. Paul's plan for Wisteria Lane is finally revealed.

Paul's nefarious plan for Wisteria Lane is put into full effect. Juanita discovers that she isn't Gabrielle's biological daughter, and Bree invites Keith to move in with her, whilst Tom is confronted about his past indiscretion with Renee.

Susan's life hangs in the balance after being trampled by the rioting mob on Wisteria Lane; the fate of Paul Young is revealed following the aftermath of the riot, but who shot him?; Keith moves in with Bree but is shocked when Orson pays a surprise visit; Gaby finds it difficult to purge all traces of Grace from her life in order to repair her relationship with Juanita; and Renee wrestles with telling Lynette the truth about her past with Tom.

While Susan continues to undergo dialysis, she is stunned when her flighty mother, Sophie, along with her aunt Claire, pays a visit but won't agree to get tested to see if she would be a potential kidney donor candidate.

Lynette feels her mother is marrying Frank, an abrasive and obnoxious man, for all the wrong reasons, and thus tries to talk her out of it. Meanwhile, Carlos becomes concerned when he learns about Gabrielle's obsession with her doll, and Bob and Lee hire a non-maternal Renee to decorate their newly adopted girl's bedroom.

Lynette fights back when her mother tries to force the Scavos to pose for a family portrait with her obnoxious new husband, Frank. Meanwhile, Susan is presented with a kidney donation from an unlikely source.

Lynette and Tom feel that it's time for twins Porter and Preston to move out on their own and learn how to become responsible adults... but the boys end up moving out to a pad that's a little too close to home. Meanwhile, as part of Gabrielle's therapy, she and Carlos pay a visit to her hometown to confront her past and discover that she has left a lasting impression on the town.

Susan vows to get the most out of life when she learns that her dialysis isn't working and that, unless she receives a kidney transplant soon, she will die. Bree makes it her mission to find a kidney donor for Susan and, jealous of Lee and Bob's adopted daughter's routine for an upcoming school talent show, Gabrielle pressures Juanita to come up with a number that will outshine everyone.

Paul Young stands in the way of Susan getting her much-needed kidney transplant; Lynette is furious with Tom when he passes up a lucrative job opportunity in order to continue working with Carlos out of friendship; Bree becomes concerned over Andrew's escalating alcohol consumption; and Gaby is shocked when Renee continues as planned with her neighborhood party after the tragic sleeping attempt of one of Wisteria Lane's resident.

Susan starts gambling; Bree tries to stop Andrew from making a confession; Felicia moves back into the neighborhood and tries to form a truce with Paul.

Gabrielle must meet Bree under a cloak of secrecy when Carlos forbids their friendship after learning the truth about his mother's passing.

With Gabrielle and her girls temporarily staying at Bree's house, Bree must lay down the law and demand discipline before Juanita and Celia destroy her home.

Paul begins to suspect that Susan is responsible for his rapidly declining health, and Lynette and Tom butt heads over where to go on their family vacation, as well as which one of them will set it up.

Gabrielle is stunned to learn the identity of the mysterious man who has been stalking her, Lynette and Tom attempt to put the spark back into their marriage by spending a few days alone together at a romantic B&B, and, after being placed under arrest for allegedly poisoning Paul, Susan must convince the police that she was being framed for the deed by Felicia.

Meanwhile, Bree begins to suspect that her new boyfriend may be gay, Renee is devastated when she learns that her ex-husband is getting re-married, and a big dinner party thrown in honor of one of the ladies results in a shocking cuddle, on the two-hour season finale of "Desperate Housewives".