Eight All-Stars teams take off from their Pit Stop at the Playa Petrohue and receive a clue instructing them to fly 800 miles to Punta Arenas, Chile and then take taxi fifteen miles to Lord Lansdale's shipwreck. The teams arrive on two flights and take part in a Detour, where lack of attention-to-detail allows teams on a later flight to catch up to teams that had gained a lead. One team experiences a near-meltdown during the Detour, but regroups and rallies by switching tasks. Meanwhile, a previous top team finds itself falling behind. The teams take two charter flights leaving three hours apart and find themselves faced with a Roadblock that requires one member of each team to sort through mail. As reward, each team receives a message from a past team, some negative and some positive. One team lies to another, hoping to gain an advantage. This team, however, is ultimately unable to recover from falling behind and is eliminated from the race.

When Homer accidentally declares bankruptcy, Grandpa ends up leaving the Springfield Retirement Castle and falls in love with Selma; Bart and Lisa con a delivery man out of cardboard boxes.

The ten remaining candidates try to prove they've got game by producing a halftime show at a soccer match. Kinetic produces the better show for the win. For their reward, they enjoyed golf time with the Donald. Arrow went to the boardroom, where Surya was fired.

When a body is found in a dumpster, the team re-opens the 1984 case of a murdered teenage boy who wanted to become a dancer against his father's wishes.

Peter helps Bill Clinton with his flat tire, and they soon become friends. They begin spending a lot of time together and Lois begins to believe that Bill is inflicting bad influence on Peter. But when she confronts Bill, they end up having sex. Peter, upset that his wife would do this, tries to get back at Lois by having an affair of his own, but soon realizes that he loves her too much to do so. Meanwhile, Lois and Stewie try to potty-train Brian.

The girls spend a day at the horse tracks where Catherine and Helena risk it all. Max takes Grace home to meet his estranged family. Bette hosts a dinner party but her obsession over every detail gets on Jodi's nerves. Meanwhile, Jenny and Tina agree on a director, Kate Arden, who quickly becomes interested in Tina.

Octavian proclaims a new era of virtue in Rome, a program that his family and subordinates find impossible to obey. Vorenus is sent on a mission after a missing shipment of gold to discover who mysteriously hijacked it on its way to the Roman treasury. Pullo's loss and rage are channeled against Memmio, Omnipor and their henchmen. Octavian pursues Livia as an "appropriate" bride, and issues Mark Antony an ultimatum he knows he can't refuse.

When a young woman is killed outside of Harry's door, Harry is drawn into finding a mysterious thieving ring where the thieves are local college students... and using black magic to walk through walls. As the students start dying one by one, something evil grows stronger, and it won't rest until all the students are dead.

When Baltar's representatives face assassination attempts, Adama asks Lee to protect Baltar's lawyer. After taking on the assignment, Lee seeks to play an active role in Baltar's defense.

A newly elected senator goes missing and Jack immediately turns his attention towards her husband.

One late evening Vicki witnesses a gruesome murder except because of her bad sight, shes not really sure what she saw. She itches to get back to what she does best, solving crimes, but her old colleague, police detective Mike Cellucci warns her against getting involved. Meanwhile, Henry Fitzroy, a vampire living in Toronto, also decides to look into the murders lest they be blamed on a vampire himself for example.

Vicki and Henry team up to solve the case and Vicki acquires an assistant, Coreen Fennel.

After teaming up with Henry Fitzroy, it's up to Vicki and Henry to find out who raised this demon.