A dog follows Brenda home from a jog. She tries desperately to find the animal a home so that she won't have to take it to a shelter. Brandon and Steve must take over Jim's little league team after he injures his back during infield practice. Brandon is disgusted with the whole experience, particularly the undue influence of the league president (father of the star pitcher) and the players' attitudes. He arranges a practice game with Nat's team of underprivileged kids, where one of his players taunts the hapless second baseman. Brandon stomps off when Steve won't let him remove the boy from the lineup. He stays with the team out of loyalty to his father, but also helps Nat's squad. The fortunes of Nat's team begin to turn around when Andrea brings in a female superstar.

With Miss Hoover out sick, an influential substitute teacher takes over for Lisas class. Meanwhile, Bart runs for class president against Martin Prince.

Sam enters a whole new world when he babysits for Frasier and Lilith, and Woody worries about Kelly when she goes to work at Cheers as part of a school project.

George goes to the doctor after he had what he thought was a heart attack. The doctor tells him that he didn't have a heart attack, but needs to get his tonsils and adenoids removed. When the cost of the surgery is too much for George, Kramer suggests that he goes on a holistic healer, but the healer turns George's skin purple and he's forced to go to the hospital. Meanwhile, George's doctor catches Elaine's eye, but he's only interested in kissing her.