Lou isn't pleased when a neighbouring rancher brings a pregnant mare named Melody to stay at Heartland. Ty is astonished when Jack asks him to join him on a cattle roundup.

The remaining four teams take off from their Pit Stop at the Bandra Fort, a nearly 500-year-old fort in Mumbai, India built by the Portuguese, and receive a clue instructing them to fly nearly 4,000 miles to Osaka, Japan. Once in Japan, teams travel to Kishiwata Castle by taxi, where they find another clue instructing them travel by taxi to Noda Station and locate a cleaning man who has their next clue. The clue gives details for a Roadblock task that requires one member of each team to become a taxi driver and do a taxing taxi drive through the streets of Osaka. Upon completing the task, racers return to their partners with the clue, which instructs them to travel to the sixteenth century Buddhist Kita-Mido Temple. The next task they face is a Detour requiring them to either sniff out flowers or take part in a robotic soccer match. In the end, one team makes a critical mistake in boarding a flight that arrives over three hours after the other teams' flight. They arrive in Osaka, complete the tasks, and receive surprising but pleasant news upon arriving at the leg's Pit Stop, Tempozan Park.

In an effort to raise money with a bond issue Mayor Quimby moves up election day, making Springfield's primary election the first in the nation causing the media, candidates and political pundits to descend in the city.

Katie and Jesse join their classmates for a trip into the African bush, but rebellious Jesse refuses to participate in the activities, while Katie and Tumelo get lost in a cave. Meanwhile, one of Jo's friends (Cynthia Watros) from New York visits and has very strong opinions about Jo's move to Africa.

Ladybird starts acting strange and bites Hank. After she's put on a vicious dog list, Hank is urged by a veterinarian to take Ladybird to a "dog spiritualist."

After a big fight between Stan and Roger, Francine comes up with a plan to try and reunite the pair. Hoping to show Roger that Stan still cares about him, Francine fakes Roger's kidnapping, but when Stan never shows up to pay the ransom, it forces Roger to rethink the way he treats people.

The team re-opens the 1999, 2001, and 2003 pipe bombing incidents that killed two and blinded one victim. The serial bomber is still on the loose and ready to strike again as he missed his latest target.

In the aftermath of the tornado, the residents of Wisteria Lane try to rebuild their lives. Katherine discovers someone may know her secret while Lynette faces the possibility of her family's fate. Meanwhile Mrs. McCluskey has to face the death of one of her dearest friends, Ida.

Following the events of the season finale, Helena is imprisoned and no one can get a hold of her mother. Jenny finds a rich investor and schemes her way to directing Lez Girls the movie. Shane is about to sign a lease on a house with Paige. The Planet hosts a coming-out party for Phyllis, where Alice and Shane attempt to hook Tina up with someone who isn't Bette. Meanwhile, Bette is waiting for Jodi to come back home from New York.

"The bigger the lie, the more they believe". - Bunk Moreland

As McNulty and the detail continue to stake out Marlo's crew, recently promoted Sgt. Carver is welcomed by a cauldron of discontent from officers coping with unpaid overtime; Though he wants to keep his campaign promise to lower crime, Mayor Carcetti is strapped by his commitment to schools, and faces some tough choices; Col. Daniels is forced to reallocate his resources, retaining Freamon and Sydnor for the Clay Davis probe; Meanwhile, city editor Augustus "Gus" Haynes and the staff of The Baltimore Sun are reeling from corporate cutbacks, losing key personnel from both the metro and international divisions; Still, with the help of reporters Alma Gutierrez, Jeff Price and Scott Templeton, Haynes is able to break a front-page story that links a politician to a co-op drug dealer; Proposition Joe, Marlo, Fatface Rick and other new day co-op members meet in a hotel conference room to discuss divvying up drug frontiers across East Baltimore's county line.

Mia and Jack Cutting are the "it" New York power couple. Newly engaged, the two must go head-to-head in a cutthroat competition to see who will be promoted to U.S. Group Publisher at Barnstead Media Group. Caitlin must deal with her new-found feelings for a person in her office. Meanwhile, Juliet lands on a unique punishment for Davis' straying. Elsewhere, Zoe and her husband, Eric, struggle to balance their careers, parenthood and marriage.