After breaking up with Eddie, Jackie tries to reconnect with her family. However, Jackie is soon on the verge of losing it when Cooper files a formal complaint against her, Eddie overdoses and she runs dry of drugs.
Without Jackie's knowledge, Eddie keeps up his friendship with Jackie's husband Kevin. In the meantime, Jackie has to cover for O'Hara who drank a little too much over her grief.
O'Hara offers financial help, but Jackie and Kevin refuse to take it. Eddie and Kevin's secret friendship is revealed.
When a patient is suffering, Jackie supplies the patient with illegal marijuana to ease the pain. Meanwhile, Kevin prevers going out with Eddie rather than spend the night with Jackie and Zoey believes she is pregnant.
Jackie's life gets a little more complicated because of a security guard and O'Hara's longtime affair comes to light.
Unhappy about Eddie and Kevin's friendship, Jackie asks Eddie to stop spending time with Kevin. A pharmaceutical company rep provides Jackie with drugs.
Coop insults the biggest donor of the hospital while Jackie revisits her affair with Eddie.
Coop arranges a date for Georgia and Eddie while Jackie's daughter Grace starts therapy.
In order to keep her secret credit card a secret, Jackie sets up a P.O. box for the credit card bills. In the meantime, Mrs. Akalitus offers Eddie to come back as the hospital's pharmacist.
In order to get a phony prescription, Jackie falsifies an MRI. In the meantime the campaign's end has its effects on Coop and Eddie is back as the hospital's pharmacist.
Jackie has to confess that she used O'Hara's loan when her stash gets lost
When Jackie comes back to work from a vacation with her family, she finally has to face Eddie, Dr. O'Hara who found out about an MRI Jackie falsified, and a drug dealer whose stash Jackie took.