Jackie has to deal with a rough intervention after her family found out about her drug addiction.

Eddie is considering telling Kevin about his affair with Jackie. Meanwhile, Jackie finds out that Dr. O'Hara wants to take new job.

Kevin's sister stops by to pay Jackie and her family a visit. In the meantime, Lenny makes plans for a romantic picnic for Zoey and Mrs. Akalitus has to deal with Catholic bureaucrats.

Jackie and Dr. O'Hara settle their difference, and Kevin asks Eddie to come to their barbecue.

Jackie runs out of drugs and Dr. Cooper decides to compete with Dr. O'Hara for the E.R. chief position.

The statues of the saints are finally removed from the chapels. Meanwhile, Jackie clashes with the new nurse named Kelly Slater and Eddie considers going out with Tunie.

The new nurse Kelly charms the hospital's staff except Jackie, meanwhile a patient eases Dr. Cooper's pain who is depressed about the split of his parents. Kevin discovers a secret stash in a dental floss dispenser while Jackie steals drugs from the Oncology.

Jackie criticizes Kelly's interaction with two flirty high school girls while Mrs. Akalitus seeks Thor's help with a new phone system. Jackie can't arrive in time at her daughter's pageant.

Just when Jackie has run out of pills, she runs into a confrontation about the drugs from Oncology that disappeared. Coop tracks down an old girlfriend on Facebook when he decides to start his own family. Heart problems make Zoey revisit her relationship with Lenny.

Grace asks her psychologist to be put on medication; Jackie is placed on probation over the drugs she stole from Oncology; Coop reserves the chapel for a wedding.

O'Hara agrees to help Jackie dose down under her supervision; Kevin is evasive and edgy with both his wife and Eddie; Akalitus loses the First Lady visit; Zoey throws a Nurse's Appreciation Week party; Kelly confesses he is responsible for Jackie's probation.

Jackie dodges Akalitus's request for a urine sample and forgets to order a cake for Coop's wedding; Kevin makes a stunning confession that leads to a marital split; Coop's bride stands him up at the altar.